BET1L - Bet1 golgi vesicular membrane trafficking protein like Gene

Homo sapiens

Also known as GS15; BET1L1; GOLIM3; HSPC197

Gene ID: 51272 | Gene type: protein coding

About BET1L

Cytogenetic location: 11p15.5 Genomic coordinates (GRCh38): 11:202,924-207,399 (from NCBI)

This gene has 7 transcripts (splice variants) and 185 orthologues. Ubiquitous expression in ovary (RPKM 28.0), thyroid (RPKM 22.6) and 25 other tissues.

Summary

Enables SNAP receptor activity. Involved in regulation of retrograde vesicle-mediated transport, Golgi to ER and retrograde transport, endosome to Golgi. Located in Golgi apparatus and endosome. Implicated in uterine fibroid. Biomarker of endometrial adenocarcinoma. [provided by Alliance of Genome Resources, Apr 2022]

BET1L Products(2)

mRNA	Protein	Name
NM_001098787.2	NP_001092257.1	BET1-like protein isoform 1
NM_016526.5	NP_057610.2	BET1-like protein isoform 2

BET1L Protein Structure

SNARE

0
100
111 a.a.

Protein Preferred Names

Protein Names

BET1-like protein

GOS-15

Related Diseases

Diseases

Alias

Endometrial Adenocarcinoma

Endometrial Endometrioid Adenocarcinoma	Endometrial Adenoacanthoma
Endometrial Endometrioid Adenocarcinoma, Variant With Squamous Differentiation	Adenocarcinoma Of Endometrium
Adenocarcinoma Of The Endometrium	Adenocarcinoma Of Uterus
Endometrial Endometrioid Adenocarcinoma With Squamous Differentiation	Endometrioid Adenoma Or Carcinoma
Endometrioid Adenomas And Carcinomas	Endometrioid Carcinoma Of Endometrium
Endometrium Adenocarcinoma

Uterine Benign Neoplasm

Reproductive Organ Benign Neoplasm

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01479	BET1L Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	BET1L	VGNC	VGNC:60105
Macaca mulatta	BET1L	VGNC	VGNC:70347
Canis familiaris	BET1L	VGNC	VGNC:38438
Rattus norvegicus	BET1L	RGD	RGD:71051
Bos taurus	BET1L	VGNC	VGNC:26476
Mus musculus	BET1L	MGD	MGI:1913128

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