2. Gene
  3. ISYNA1 - inositol-3-phosphate synthase 1 Gene

ISYNA1 - inositol-3-phosphate synthase 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as IPS; INO1; INOS; IPS 1; IPS-1

Gene ID: 51477 | Gene type: protein coding

About ISYNA1

Cytogenetic location: 19p13.11 Genomic coordinates (GRCh38): 19:18,434,388-18,438,133 (from NCBI)

This gene has 14 transcripts (splice variants) and 208 orthologues. Broad expression in testis (RPKM 72.6), placenta (RPKM 57.0) and 14 other tissues.

Summary

This gene encodes an inositol-3-phosphate synthase Enzyme. The encoded protein plays a critical role in the myo-inositol biosynthesis pathway by catalyzing the rate-limiting conversion of glucose 6-phosphate to myoinositol 1-phosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011]

ISYNA1 Products(3)

mRNA Protein Name
NM_001170938.2 NP_001164409.1 inositol-3-phosphate synthase 1 isoform 2
NM_001253389.2 NP_001240318.1 inositol-3-phosphate synthase 1 isoform 4
NM_016368.5 NP_057452.1 inositol-3-phosphate synthase 1 isoform 1

ISYNA1 Protein Structure

NAD_binding_5

NAD_binding_5: Myo-inositol-1-phosphate synthase (59 - 491)

Inos-1-P_synth

Inos-1-P_synth: Myo-inositol-1-phosphate synthase (307 - 420)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 558 a.a.
Protein Preferred Names Protein Names

inositol-3-phosphate synthase 1

MI-1-P synthase

Related Diseases

Diseases Alias
Lidocaine Allergy

Lidoderm Allergy

Lignocaine Allergy

Xylocaine Allergy
Nemaline Myopathy 1

Cap Myopathy 1

NEM1

Nemaline Myopathy 1, Autosomal Dominant Or Recessive

Nemaline Myopathy, Type 1

CAPM1

Cap Disease

Cap Myopathy Tpm3-Related

Nemaline Myopathy 1 Autosomal Dominant Or Recessive

Myopathy, Nemaline, Type 1

Cap Myopathy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06942 ISYNA1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ISYNA1 VGNC VGNC:73685
Bos taurus ISYNA1 VGNC VGNC:30306
Canis familiaris ISYNA1 VGNC VGNC:42116
Mus musculus ISYNA1 MGD MGI:1919030
Rattus norvegicus ISYNA1 RGD RGD:1359423
Felis catus ISYNA1 VGNC VGNC:62982