2. Gene
  3. RAB6B - RAB6B, member RAS oncogene family Gene

RAB6B - RAB6B, member RAS oncogene family Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 51560 | Gene type: protein coding

About RAB6B

Cytogenetic location: 3q22.1 Genomic coordinates (GRCh38): 3:133,824,235-133,895,882 (from NCBI)

This gene has 7 transcripts (splice variants), 249 orthologues and 68 paralogues. Biased expression in brain (RPKM 76.4), heart (RPKM 6.6) and 1 other tissue.

Summary

Enables Myosin V binding activity. Predicted to be involved in Golgi vesicle transport; intracellular protein transport; and retrograde transport, endosome to Golgi. Located in Golgi apparatus. [provided by Alliance of Genome Resources, Apr 2022]

RAB6B Products(2)

mRNA Protein Name
NM_001363953.1 NP_001350882.1 ras-related protein Rab-6B isoform 2
NM_016577.4 NP_057661.3 ras-related protein Rab-6B isoform 1

RAB6B Protein Structure

Ras

Ras: Ras family (15 - 173)

  • 0
  • 100
  • 208 a.a.
Protein Preferred Names Protein Names

ras-related protein Rab-6B

small GTP-binding protein

Related Diseases

Diseases Alias
Cohen Syndrome

Pepper Syndrome

COH1

Hypotonia, Obesity, And Prominent Incisors

Coh

Chs1, Formerly

Norio Syndrome

Obesity-Hypotonia Syndrome

Prominent Incisors-Obesity-Hypotonia Syndrome

Chs1

Hypotonia-Obesity-Prominent Incisors

Stage 4s Neuroblastoma
Charcot-Marie-Tooth Disease, Recessive Intermediate A

Charcot-Marie-Tooth Disease Recessive Intermediate A

CMTRIA

Ri-Cmta

Charcot-Marie-Tooth Disease, Recessive Intermediate, A

Autosomal Recessive Intermediate Charcot-Marie-Tooth Disease Type A

Charcot-Marie-Tooth Neuropathy Recessive Intermediate A

Charcot-Marie-Tooth Neuropathy, Recessive Intermediate A

Ri-Cmt Type A

Charcot-Marie-Tooth Disease, Recessive, Intermediate Type, A
Corneal Dystrophy, Fleck

Fleck Corneal Dystrophy

Fcd

CFD

Corneal Fleck Dystrophy

Francois-Neetens Speckled Corneal Dystrophy

Corneal Dystrophy, Francois-Neetens Speckled Or Flecked

Corneal Dystrophy Francois-Neetens Speckled Or Flecked

Dystrophy, Corneal, Fleck
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11575 RAB6B Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris RAB6B VGNC VGNC:59057
Bos taurus RAB6B VGNC VGNC:50013
Rattus norvegicus RAB6B RGD RGD:1309958
Mus musculus RAB6B MGD MGI:107283
Macaca mulatta RAB6B VGNC VGNC:81547