2. Gene
  3. SLC25A39 - solute carrier family 25 member 39 Gene

SLC25A39 - solute carrier family 25 member 39 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CGI69; CGI-69

Gene ID: 51629 | Gene type: protein coding

About SLC25A39

Cytogenetic location: 17q21.31 Genomic coordinates (GRCh38): 17:44,319,628-44,324,823 (from NCBI)

This gene has 17 transcripts (splice variants), 143 orthologues and 49 paralogues. Ubiquitous expression in bone marrow (RPKM 112.9), kidney (RPKM 47.3) and 25 other tissues.

Summary

This gene encodes a member of the SLC25 transporter or mitochondrial carrier family of proteins. Members of this family are encoded by the nuclear genome while their protein products are usually embedded in the inner mitochondrial membrane and exhibit wide-ranging substrate specificity. Although the encoded protein is currently considered an orphan transporter, this protein is related to other carriers known to transport Amino acids. This protein may play a role in iron homeostasis. [provided by RefSeq, Mar 2016]

SLC25A39 Products(5)

mRNA Protein Name
NM_001143780.3 NP_001137252.1 probable mitochondrial glutathione transporter SLC25A39 isoform a
NM_001321240.2 NP_001308169.1 probable mitochondrial glutathione transporter SLC25A39 isoform c
NM_001321241.2 NP_001308170.1 probable mitochondrial glutathione transporter SLC25A39 isoform d
NM_001366726.1 NP_001353655.1 probable mitochondrial glutathione transporter SLC25A39 isoform e
NM_016016.4 NP_057100.1 probable mitochondrial glutathione transporter SLC25A39 isoform b

SLC25A39 Protein Structure

Mito_carr

Mito_carr: Mitochondrial carrier protein (9 - 152)

Mito_carr

Mito_carr: Mitochondrial carrier protein (161 - 245)

Mito_carr

Mito_carr: Mitochondrial carrier protein (253 - 350)

  • 0
  • 100
  • 200
  • 300
  • 359 a.a.
Protein Preferred Names Protein Names

probable mitochondrial glutathione transporter SLC25A39

Related Diseases

Diseases Alias
Combined Oxidative Phosphorylation Deficiency 18

Growth And Developmental Delay-Hypotonia-Vision Impairment-Lactic Acidosis Syndrome

COXPD18

Combined Oxidative Phosphorylation Deficiency, Type 18
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13121 SLC25A39 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SLC25A39 VGNC VGNC:34764
Canis familiaris SLC25A39 VGNC VGNC:49801
Rattus norvegicus SLC25A39 RGD RGD:1306193
Mus musculus SLC25A39 MGD MGI:1196386
Felis catus SLC25A39 VGNC VGNC:65274
Macaca mulatta SLC25A39 VGNC VGNC:77568