PPIL1 - peptidylprolyl isomerase like 1 Gene

Homo sapiens

Also known as CYPL1; PCH14; hCyPX; PPIase; CGI-124

Gene ID: 51645 | Gene type: protein coding

About PPIL1

Cytogenetic location: 6p21.2 Genomic coordinates (GRCh38): 6:36,854,829-36,874,803 (from NCBI)

This gene has 2 transcripts (splice variants), 215 orthologues, 22 paralogues and is associated with 2 phenotypes. Ubiquitous expression in adrenal (RPKM 23.5), thyroid (RPKM 20.4) and 25 other tissues.

Summary

This gene is a member of the cyclophilin family of peptidylprolyl isomerases (PPIases). The cyclophilins are a highly conserved, ubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and Infection of HIV-1 virions. Based on similarity to other PPIases, this protein could accelerate the folding of proteins and might catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. [provided by RefSeq, Jul 2008]

PPIL1 Products(1)

mRNA	Protein	Name
NM_016059.5	NP_057143.1	peptidyl-prolyl cis-trans isomerase-like 1

PPIL1 Protein Structure

Pro_isomerase

0
100
166 a.a.

Protein Preferred Names

Protein Names

peptidyl-prolyl cis-trans isomerase-like 1

cyclophilin like 1

Recombinant PPIL1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71226	PPIL1 Protein, Human (His)	Q9Y3C6 (M1-G166)	≥95%

Related Diseases

Diseases

Alias

Pontocerebellar Hypoplasia, Type 14

PCH14	Pontocerebellar Hypoplasia Type 14
Pontocerebellar Hypoplasia 14	Doid:0112325

Pontocerebellar Hypoplasia

Pch	Congenital Pontocerebellar Hypoplasia
Opch	Hypoplasia, Pontocerebellar
Pontoneocerebellar Hypoplasia	Nonsyndromic Pontocerebellar Hypoplasia

Spastic Quadriplegia

Spastic Quadriplegic Cerebral Palsy	Quadriplegic Infantile Cerebral Palsy
Tetraplegic Infantile Cerebral Palsy	Cerebral Palsy Spastic Quadriplegic
Quadriplegic Cerebral Palsy	Spastic Quadriplegia Cerebral Palsy
Spastic Tetraplegia Cerebral Palsy	Cerebral Palsy, Quadriplegic, Infantile
Cerebral Palsy With Spastic Tetraplegia	Congenital Spastic Quadriplegia
Spastic Tetraplegic Cerebral Palsy	Congenital Quadriplegia Nos
Tetraplegic Cerebral Palsy

Quadriplegia

Tetraplegia

Tetraplegias

Microcephaly

Microencephaly	Microcephalus
Microcephalic	Nanocephaly
Congenital Microcephaly	Brain Hypoplasia
Brain Nondevelopment	Cephalic Hypoplasia
Undeveloped Cerebrum	Undeveloped Brain
Micrencephalon	Micrencephaly

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10954	PPIL1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	PPIL1	VGNC	VGNC:102486
Rattus norvegicus	PPIL1	RGD	RGD:1309119
Bos taurus	PPIL1	VGNC	VGNC:33201
Mus musculus	PPIL1	MGD	MGI:1916066
Macaca mulatta	PPIL1	VGNC	VGNC:104420
Canis familiaris	PPIL1	VGNC	VGNC:44855
Others	PPIL1	NCBI

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