2. Gene
  3. MRPS23 - mitochondrial ribosomal protein S23 Gene

MRPS23 - mitochondrial ribosomal protein S23 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CGI-138; COXPD46; HSPC329; MRP-S23

Gene ID: 51649 | Gene type: protein coding

About MRPS23

Cytogenetic location: 17q22 Genomic coordinates (GRCh38): 17:57,834,781-57,850,044 (from NCBI)

This gene has 4 transcripts (splice variants), 193 orthologues and is associated with 1 phenotype. Ubiquitous expression in heart (RPKM 19.2), prostate (RPKM 17.3) and 25 other tissues.

Summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 7p. [provided by RefSeq, Jul 2008]

MRPS23 Products(1)

mRNA Protein Name
NM_016070.4 NP_057154.2 28S ribosomal protein S23, mitochondrial

MRPS23 Protein Structure

MRP-S23

MRP-S23: Mitochondrial ribosomal protein S23 (2 - 132)

  • 0
  • 100
  • 190 a.a.
Protein Preferred Names Protein Names

28S ribosomal protein S23, mitochondrial

S23mt

Related Diseases

Diseases Alias
Combined Oxidative Phosphorylation Deficiency 46

COXPD46
Colorectal Cancer, Hereditary Nonpolyposis, Type 7

HNPCC7

Hereditary Nonpolyposis Colorectal Cancer Type 7

Hereditary Non-Polyposis Colorectal Cancer 7

Cancer, Colorectal, Nonpolyposis, Hereditary, Type 7
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08680 MRPS23 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus MRPS23 RGD RGD:1306963
Mus musculus MRPS23 MGD MGI:1928138
Bos taurus MRPS23 VGNC VGNC:31663
Felis catus MRPS23 VGNC VGNC:99283
Macaca mulatta MRPS23 VGNC VGNC:99173
Canis familiaris MRPS23 VGNC VGNC:43415