2. Gene
  3. PIN4 - peptidylprolyl cis/trans isomerase, NIMA-interacting 4 Gene

PIN4 - peptidylprolyl cis/trans isomerase, NIMA-interacting 4 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as EPVH; PAR14; PAR17

Gene ID: 5303 | Gene type: protein coding

About PIN4

Cytogenetic location: Xq13.1 Genomic coordinates (GRCh38): X:72,181,676-72,263,964 (from NCBI)

This gene has 9 transcripts (splice variants), 231 orthologues and 1 paralogue. Ubiquitous expression in liver (RPKM 5.5), kidney (RPKM 4.8) and 25 other tissues.

Summary

This gene encodes a member of the parvulin subfamily of the peptidyl-prolyl cis/trans isomerase protein family. The encoded protein catalyzes the isomerization of peptidylprolyl bonds, and may play a role in the cell cycle, chromatin remodeling, and/or ribosome biogenesis. The encoded protein may play an additional role in the mitochondria. [provided by RefSeq, Dec 2009]

PIN4 Products(2)

mRNA Protein Name
NM_001170747.1 NP_001164218.1 peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 isoform 2
NM_006223.4 NP_006214.3 peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 isoform 1

PIN4 Protein Structure

Rotamase_3

Rotamase_3: PPIC-type PPIASE domain (59 - 156)

  • 0
  • 100
  • 156 a.a.
Protein Preferred Names Protein Names

peptidyl-prolyl cis-trans isomerase NIMA-interacting 4

PPIase PIN4

Recombinant PIN4 Proteins

Cat. No. Product Name Accession Purity
HY-P71205 PIN4 Protein, Human (His) Q9Y237-2 (M1-K156) ≥95%

Related Diseases

Diseases Alias
Prostatic Acinar Adenocarcinoma

Acinar Prostate Adenocarcinoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10558 PIN4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus PIN4 VGNC VGNC:103741
Bos taurus PIN4 VGNC VGNC:32903
Rattus norvegicus PIN4 RGD RGD:1590326
Mus musculus PIN4 MGD MGI:1916963
Others PIN4 NCBI