CPSF2 - cleavage and polyadenylation specific factor 2 Gene

Homo sapiens

Also known as CPSF100

Gene ID: 53981 | Gene type: protein coding

About CPSF2

Cytogenetic location: 14q32.12 Genomic coordinates (GRCh38): 14:92,121,969-92,172,145 (from NCBI)

This gene has 5 transcripts (splice variants), 210 orthologues and 3 paralogues. Ubiquitous expression in testis (RPKM 13.0), thyroid (RPKM 12.9) and 25 other tissues.

Summary

Predicted to enable RNA binding activity. Involved in mRNA 3'-end processing by stem-loop binding activity and cleavage. Located in membrane. Part of mRNA cleavage and polyadenylation specificity factor complex. [provided by Alliance of Genome Resources, Apr 2022]

CPSF2 Products(4)

mRNA	Protein	Name
NM_001322270.2	NP_001309199.1	cleavage and polyadenylation specificity factor subunit 2 isoform 2
NM_001322271.2	NP_001309200.1	cleavage and polyadenylation specificity factor subunit 2 isoform 3
NM_001322272.2	NP_001309201.1	cleavage and polyadenylation specificity factor subunit 2 isoform 1
NM_017437.3	NP_059133.1	cleavage and polyadenylation specificity factor subunit 2 isoform 1

CPSF2 Protein Structure

Lactamase_B

Beta-Casp

RMMBL

CPSF100_C

0
200
400
600
782 a.a.

Protein Preferred Names

Protein Names

cleavage and polyadenylation specificity factor subunit 2

CPSF 100 kDa subunit

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03117	CPSF2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	CPSF2	VGNC	VGNC:61140
Canis familiaris	CPSF2	VGNC	VGNC:39574
Bos taurus	CPSF2	VGNC	VGNC:27671
Macaca mulatta	CPSF2	VGNC	VGNC:71473
Mus musculus	CPSF2	MGD	MGI:1861601
Rattus norvegicus	CPSF2	RGD	RGD:1309687

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