SASH3 - SAM and SH3 domain containing 3 Gene

Homo sapiens

Also known as SLY; 753P9; HACS2; CXorf9; IMD102; SH3D6C

Gene ID: 54440 | Gene type: protein coding

About SASH3

Cytogenetic location: Xq26.1 Genomic coordinates (GRCh38): X:129,779,949-129,795,201 (from NCBI)

This gene has 2 transcripts (splice variants), 196 orthologues and 2 paralogues. Biased expression in lymph node (RPKM 60.1), spleen (RPKM 41.7) and 11 other tissues.

Summary

The protein encoded by this gene contains a Src homology-3 (SH3) domain and a sterile alpha motif (SAM), both of which are found in proteins involved in cell signaling. This protein may function as a signaling adapter protein in lymphocytes.[provided by RefSeq, Sep 2009]

SASH3 Products(1)

mRNA	Protein	Name
NM_018990.4	NP_061863.1	SAM and SH3 domain-containing protein 3

SASH3 Protein Structure

SLY

SH3_2

SAM_2

0
100
200
300
380 a.a.

Protein Preferred Names

Protein Names

SAM and SH3 domain-containing protein 3

SH3 protein expressed in lymphocytes homolog

Related Diseases

Diseases

Alias

Immunodeficiency 102

IMD102

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12453	SASH3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SASH3	VGNC	VGNC:77022
Felis catus	SASH3	VGNC	VGNC:64879
Bos taurus	SASH3	VGNC	VGNC:34294
Mus musculus	SASH3	MGD	MGI:1921381
Canis familiaris	SASH3	VGNC	VGNC:45872
Rattus norvegicus	SASH3	RGD	RGD:1560293

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