2. Gene
  3. RC3H2 - ring finger and CCCH-type domains 2 Gene

RC3H2 - ring finger and CCCH-type domains 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as MNAB; RNF164

Gene ID: 54542 | Gene type: protein coding

About RC3H2

Cytogenetic location: 9q33.2 Genomic coordinates (GRCh38): 9:122,844,556-122,905,359 (from NCBI)

This gene has 10 transcripts (splice variants), 206 orthologues and 5 paralogues. Ubiquitous expression in lymph node (RPKM 7.8), testis (RPKM 7.6) and 25 other tissues.

Summary

Enables nucleic acid binding activity and ubiquitin protein ligase activity. Involved in protein polyubiquitination. Located in cell surface; intracellular membrane-bounded organelle; and membrane. [provided by Alliance of Genome Resources, Apr 2022]

RC3H2 Products(6)

mRNA Protein Name
NM_001100588.3 NP_001094058.1 roquin-2 isoform 1
NM_001354478.2 NP_001341407.1 roquin-2 isoform 3
NM_001354479.2 NP_001341408.1 roquin-2 isoform 4
NM_001354482.2 NP_001341411.1 roquin-2 isoform 5
NM_001354486.2 NP_001341415.1 roquin-2 isoform 6
NM_018835.5 NP_061323.2 roquin-2 isoform 2

RC3H2 Protein Structure

zf-CCCH

zf-CCCH: Zinc finger C-x8-C-x5-C-x3-H type (and similar) (411 - 437)

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  • 1191 a.a.
Protein Preferred Names Protein Names

roquin-2

RING finger protein 164

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11778 RC3H2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus RC3H2 VGNC VGNC:64541
Bos taurus RC3H2 VGNC VGNC:33819
Macaca mulatta RC3H2 VGNC VGNC:76799
Mus musculus RC3H2 MGD MGI:2442789
Rattus norvegicus RC3H2 RGD RGD:1304833