2. Gene
  3. NECAB2 - N-terminal EF-hand calcium binding protein 2 Gene

NECAB2 - N-terminal EF-hand calcium binding protein 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as EFCBP2; stip-2

Gene ID: 54550 | Gene type: protein coding

About NECAB2

Cytogenetic location: 16q23.3 Genomic coordinates (GRCh38): 16:83,965,177-84,002,776 (from NCBI)

This gene has 6 transcripts (splice variants), 196 orthologues and 2 paralogues. Biased expression in brain (RPKM 9.4), kidney (RPKM 3.0) and 3 other tissues.

Summary

The protein encoded by this gene is a neuronal calcium-binding protein that binds to and modulates the function of at least two receptors, adenosine A(2A) receptor and metabotropic glutamate receptor type 5. [provided by RefSeq, Jul 2016]

NECAB2 Products(3)

mRNA Protein Name
NM_001329748.1 NP_001316677.1 N-terminal EF-hand calcium-binding protein 2 isoform 2
NM_001329749.2 NP_001316678.1 N-terminal EF-hand calcium-binding protein 2 isoform 3
NM_019065.3 NP_061938.2 N-terminal EF-hand calcium-binding protein 2 isoform 1

NECAB2 Protein Structure

EF-hand_7

EF-hand_7: EF-hand domain pair (65 - 123)

ABM

ABM: Antibiotic biosynthesis monooxygenase (288 - 358)

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  • 386 a.a.
Protein Preferred Names Protein Names

N-terminal EF-hand calcium-binding protein 2

EF-hand calcium-binding protein 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09171 NECAB2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus NECAB2 RGD RGD:621844
Felis catus NECAB2 VGNC VGNC:63763
Mus musculus NECAB2 MGD MGI:2152211
Macaca mulatta NECAB2 VGNC VGNC:75239
Bos taurus NECAB2 VGNC VGNC:31978