MED18 - mediator complex subunit 18 Gene

Homo sapiens

Also known as SRB5; p28b

Gene ID: 54797 | Gene type: protein coding

About MED18

Cytogenetic location: 1p35.3 Genomic coordinates (GRCh38): 1:28,329,040-28,335,965 (from NCBI)

This gene has 5 transcripts (splice variants), 1 gene allele and 197 orthologues. Ubiquitous expression in colon (RPKM 5.4), lymph node (RPKM 4.8) and 25 other tissues.

Summary

MED18 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008]

MED18 Products(2)

mRNA	Protein	Name
NM_001127350.2	NP_001120822.1	mediator of RNA polymerase II transcription subunit 18
NM_017638.3	NP_060108.2	mediator of RNA polymerase II transcription subunit 18

MED18 Protein Structure

Med18

0
100
208 a.a.

Protein Preferred Names

Protein Names

mediator of RNA polymerase II transcription subunit 18

TRAP/mediator complex subunit p28b

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08289	MED18 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	MED18	VGNC	VGNC:31355
Macaca mulatta	MED18	VGNC	VGNC:74587
Mus musculus	MED18	MGD	MGI:1914469
Canis familiaris	MED18	VGNC	VGNC:43127
Rattus norvegicus	MED18	RGD	RGD:1592757

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