2. Gene
  3. NCAPG2 - non-SMC condensin II complex subunit G2 Gene

NCAPG2 - non-SMC condensin II complex subunit G2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as 3KS; MTB; CAPG2; LUZP5; CAP-G2; hCAP-G2

Gene ID: 54892 | Gene type: protein coding

About NCAPG2

Cytogenetic location: 7q36.3 Genomic coordinates (GRCh38): 7:158,631,169-158,704,804 (from NCBI)

This gene has 11 transcripts (splice variants), 213 orthologues and is associated with 2 phenotypes. Broad expression in testis (RPKM 7.7), bone marrow (RPKM 6.8) and 24 other tissues.

Summary

This gene encodes a protein that belongs to the Condensin2nSMC family of proteins. The encoded protein is a regulatory subunit of the condensin II complex which, along with the condensin I complex, plays a role in chromosome assembly and segregation during mitosis. A similar protein in mouse is required for early development of the embryo. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

NCAPG2 Products(3)

mRNA Protein Name
NM_001281932.2 NP_001268861.1 condensin-2 complex subunit G2 isoform a
NM_001281933.2 NP_001268862.1 condensin-2 complex subunit G2 isoform b
NM_017760.7 NP_060230.5 condensin-2 complex subunit G2 isoform a

NCAPG2 Protein Structure

Condensin2nSMC

Condensin2nSMC: Condensin II non structural maintenance of chromosomes subunit (210 - 363)

Condensin2nSMC

Condensin2nSMC: Condensin II non structural maintenance of chromosomes subunit (673 - 827)

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  • 1143 a.a.
Protein Preferred Names Protein Names

condensin-2 complex subunit G2

chromosome-associated protein G2

Related Diseases

Diseases Alias
Khan-Khan-Katsanis Syndrome

3KS

3k Syndrome
Peters-Plus Syndrome

Krause-Kivlin Syndrome

Peters Plus Syndrome

Peters Anomaly

Irido-Corneo-Trabecular Dysgenesis

PTRPLS

Peters Anomaly With Short-Limb Dwarfism

Peters Anomaly-Short Limb Dwarfism Syndrome

Peters Anomaly With Short Limb Dwarfism

Peters Congenital Glaucoma

Krause-Van Schooneveld-Kivlin Syndrome

Peters' Plus Syndrome

Peters'-Plus Syndrome

Anomaly Peters
Primary Microcephaly

True Microcephaly

Microcephaly, Primary
Microcephaly

Microencephaly

Microcephalus

Microcephalic

Nanocephaly

Congenital Microcephaly

Brain Hypoplasia

Brain Nondevelopment

Cephalic Hypoplasia

Undeveloped Cerebrum

Undeveloped Brain

Micrencephalon

Micrencephaly
Primary Autosomal Recessive Microcephaly

Autosomal Recessive Primary Microcephaly

Mcph

True Microcephaly

Microcephalia Vera

Microcephaly Vera

Microcephaly Primary Hereditary

Microcephaly, Primary, Autosomal Recessive

Primary Microcephaly
Congenital Nervous System Abnormality

Congenital Neurologic Anomaly

Congenital Nervous System Disorder
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09069 NCAPG2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus NCAPG2 VGNC VGNC:63733
Macaca mulatta NCAPG2 VGNC VGNC:75003
Bos taurus NCAPG2 VGNC VGNC:31904
Rattus norvegicus NCAPG2 RGD RGD:1308406
Mus musculus NCAPG2 MGD MGI:1923294
Canis familiaris NCAPG2 VGNC VGNC:43642