EXD3 - exonuclease 3'-5' domain containing 3 Gene

Homo sapiens

Also known as Nbr; mut-7

Gene ID: 54932 | Gene type: protein coding

About EXD3

This gene has 12 transcripts (splice variants), 165 orthologues and 1 paralogue. Ubiquitous expression in spleen (RPKM 2.6), fat (RPKM 2.4) and 25 other tissues.

Summary

Predicted to enable 3'-5' exonuclease activity. Predicted to be involved in nucleic acid phosphodiester bond hydrolysis. [provided by Alliance of Genome Resources, Apr 2022]

EXD3 Products(2)

mRNA	Protein	Name
NM_001286823.2	NP_001273752.1	exonuclease mut-7 homolog isoform b
NM_017820.5	NP_060290.3	exonuclease mut-7 homolog isoform a

EXD3 Protein Structure

DNA_pol_A_exo1

Mut7-C

0
200
400
600
800
876 a.a.

Protein Preferred Names

Protein Names

exonuclease mut-7 homolog

exonuclease 3'-5' domain-containing protein 3

Related Diseases

Diseases

Alias

Atrial Septal Defect 8

ASD8	Atrial Heart Septal Defect 8
Septal Defect, Atrial, Type 8

Vulto-Van Silfhout-De Vries Syndrome

Vulto-Van Silfout-De Vries Syndrome	VSVS
Intellectual Developmental Disorder With Impaired Expressive Speech And Behavioral Abnormalities, With Or Without Seizures	Iddisbas
Mrd24	Mental Retardation, Autosomal Dominant 24
Autosomal Dominant Mental Retardation 24	Autosomal Dominant Non-Syndromic Intellectual Disability 24
Mental Retardation, Autosomal Dominant, Type 24

Atrial Septal Defect 4

ASD4	Atrial Heart Septal Defect 4
Septal Defect, Atrial, Type 4

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04584	EXD3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

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