TRMT61B - tRNA methyltransferase 61B Gene

Homo sapiens

Gene ID: 55006 | Gene type: protein coding

About TRMT61B

Cytogenetic location: 2p23.2 Genomic coordinates (GRCh38): 2:28,849,821-28,870,309 (from NCBI)

This gene has 5 transcripts (splice variants), 182 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 8.4), small intestine (RPKM 6.4) and 25 other tissues.

Summary

Enables mRNA (adenine-N1-)-methyltransferase activity; rRNA (adenine) methyltransferase activity; and tRNA (adenine-N1-)-methyltransferase activity. Involved in mRNA methylation; mitochondrial tRNA methylation; and protein homooligomerization. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

TRMT61B Products(1)

mRNA	Protein	Name
NM_017910.4	NP_060380.3	tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial precursor

TRMT61B Protein Structure

GCD14

0
100
200
300
400
477 a.a.

Protein Preferred Names

Protein Names

tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial

mRNA methyladenosine-N(1)-methyltransferase

Related Diseases

Diseases

Alias

Malignant Histiocytic Disease

Histiocytic Disorders, Malignant

3-Methylcrotonyl-Coa Carboxylase 1 Deficiency

MCC1D	Mccd Type 1
Mcc1 Deficiency	Methylcrotonylglycinuria Type I
3-Methylcrotonylglycinuria I	3-Methylcrotonoyl-Coa Carboxylase 1 Deficiency
3-Methylcrotonylglycinuria Type I	Mcgi
3 Methylcrotonyl-Coa Carboxylase 1 Deficiency	3-Methylcrotonyl Coa Carboxylase 1 Deficiency

Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes

Melas Syndrome	MELAS
Mitochondrial Encephalomyopathy Lactic Acidosis And Stroke-Like Episodes	Mitochondrial Myopathy, Lactic Acidosis, Stroke-Like Episode
Mitochondrial Encephalomyopathy, Lactic Acidosis, And Stroke-Like Episodes	Myopathy, Mitochondrial-Encephalopathy-Lactic Acidosis-Stroke
Mitochondrial Encephalomyopathy, Lactic Acidosis And Stroke-Like Episodes	Mitochondrial Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes
Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis And Stroke-Like Episodes	Mitochondrial Encephalomyopathy With Lactic Acidosis And Stroke-Like Episodes Syndrome
Myopathy, Mitochondrial, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15096	TRMT61B Human Pre-designed siRNA Set A		/	Unkown

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