2. Gene
  3. NRDE2 - NRDE-2, necessary for RNA interference, domain containing Gene

NRDE2 - NRDE-2, necessary for RNA interference, domain containing Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as C14orf102

Gene ID: 55051 | Gene type: protein coding

About NRDE2

Cytogenetic location: 14q32.11 Genomic coordinates (GRCh38): 14:90,267,860-90,331,941 (from NCBI)

This gene has 10 transcripts (splice variants) and 190 orthologues. Ubiquitous expression in duodenum (RPKM 3.4), thyroid (RPKM 3.4) and 25 other tissues.

Summary

Involved in several processes, including RNA splicing; negative regulation of RNA catabolic process; and positive regulation of RNA export from nucleus. Located in nuclear speck and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

NRDE2 Products(1)

mRNA Protein Name
NM_017970.4 NP_060440.2 nuclear exosome regulator NRDE2

NRDE2 Protein Structure

NRDE-2

NRDE-2: NRDE-2, necessary for RNA interference (308 - 649)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1164 a.a.
Protein Preferred Names Protein Names

nuclear exosome regulator NRDE2

UPF0614 protein C14orf102

Related Diseases

Diseases Alias
Hypertrichosis Universalis Congenita, Ambras Type

Ambras Syndrome

Hypertrichosis, Congenital Generalized

HTC1

HTC2

Chromosome Xq27.1 Interchromosomal Insertion Syndrome

Cgh

Hcg

Ambras Type Hypertrichosis Universalis Congenita

X-Linked Congenital Generalized Hypertrichosis

Congenital Generalized Hypertrichosis, Macias-Flores Type

Macias Flores-Garcia Cruz-Rivera Syndrome

Htc 1

Hypertrichosis Universalis Congenita Ambras Type

Hypertrichosis Congenital Generalized X-Linked

Macias-Flores Garcia-Cruz Rivera Syndrome

Congenital Generalized Hypertrichosis, Ambras Type
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09565 NRDE2 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus NRDE2 VGNC VGNC:32259
Rattus norvegicus NRDE2 RGD RGD:1565082
Mus musculus NRDE2 MGD MGI:2670969
Macaca mulatta NRDE2 VGNC VGNC:75440
Canis familiaris NRDE2 VGNC VGNC:43965
Felis catus NRDE2 VGNC VGNC:63878