AKIRIN2 - akirin 2 Gene

Homo sapiens

Also known as FBI1; C6orf166; dJ486L4.2

Gene ID: 55122 | Gene type: protein coding

About AKIRIN2

Cytogenetic location: 6q15 Genomic coordinates (GRCh38): 6:87,674,860-87,702,233 (from NCBI)

This gene has 2 transcripts (splice variants), 201 orthologues and 1 paralogue. Ubiquitous expression in bone marrow (RPKM 25.3), spleen (RPKM 21.1) and 24 other tissues.

Summary

Enables Enzyme binding activity and identical protein binding activity. Predicted to be involved in positive regulation of innate immune response and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within positive regulation of interleukin-6 production and response to lipopolysaccharide. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

AKIRIN2 Products(1)

mRNA	Protein	Name
NM_018064.4	NP_060534.1	akirin-2

Protein Preferred Names

Protein Names

akirin-2

fourteen-three-three beta interactant 1

Related Diseases

Diseases

Alias

Zebrafish Allergy

Danio Rerio Allergy

Tick Infestation

Tick Infestations

Metacarpal 4-5 Fusion

Syndactyly Type 8	MF4
Fusion Of Metacarpals 4 And 5	Metacarpals 4 And 5 Fusion
Metacarpal 4 5 Fusion

Parasitic Ectoparasitic Infectious Disease

Ectoparasitic Infestations

Ectoparasitism

Lice Infestation

Pediculosis	Louse Infestation
Mixed Pediculosis	Lice Infestations
Infestation By Pediculus	Mixed Pediculosis Infestation
Pediculosis + Lice	Pediculosis And Phthirus Infection
Pediculosis And Phthirus Infections	Pediculosis And Phthirus Infestation
Infestation By Anoplura	Pediculus Infestation
Lice Nos

Tick Paralysis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00528	AKIRIN2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	AKIRIN2	VGNC	VGNC:25794
Mus musculus	AKIRIN2	MGD	MGI:1889364
Canis familiaris	AKIRIN2	VGNC	VGNC:37766
Felis catus	AKIRIN2	VGNC	VGNC:59721
Rattus norvegicus	AKIRIN2	RGD	RGD:1307791
Macaca mulatta	AKIRIN2	VGNC	VGNC:69665

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