2. Gene
  3. MSL2 - MSL complex subunit 2 Gene

MSL2 - MSL complex subunit 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as MSL-2; MSL2L1; RNF184

Gene ID: 55167 | Gene type: protein coding

About MSL2

Cytogenetic location: 3q22.3 Genomic coordinates (GRCh38): 3:136,148,917-136,196,335 (from NCBI)

This gene has 8 transcripts (splice variants), 263 orthologues and is associated with 1 phenotype. Ubiquitous expression in bone marrow (RPKM 16.6), lymph node (RPKM 11.8) and 25 other tissues.

Summary

Predicted to enable ubiquitin protein ligase activity. Involved in histone H4-K16 acetylation. Part of MSL complex. [provided by Alliance of Genome Resources, Apr 2022]

MSL2 Products(2)

mRNA Protein Name
NM_001145417.2 NP_001138889.1 E3 ubiquitin-protein ligase MSL2 isoform 2
NM_018133.4 NP_060603.2 E3 ubiquitin-protein ligase MSL2 isoform 1
Protein Preferred Names Protein Names

E3 ubiquitin-protein ligase MSL2

E3 ubiquitin-protein transferase MSL2

Related Diseases

Diseases Alias
Basilicata-Akhtar Syndrome

Mrxs36

MRXSBA

Mental Retardation, X-Linked, Syndromic, Basilicata-Akhtar Type

Mental Retardation, X-Linked, Syndromic 36

X-Linked Syndromic Mental Retardation 36

X-Linked Syndromic Mental Retardation Basilicata-Akhtar Type
Atrial Septal Defect 3

ASD3

Atrial Heart Septal Defect 3

Septal Defect, Atrial, Type 3
Koolen-De Vries Syndrome

KDVS

17q21.31 Microdeletion Syndrome

Microdeletion 17q21.31 Syndrome

Chromosome 17q21.31 Deletion Syndrome

Koolen De Vries Syndrome

Kansl1-Related Intellectual Disability Syndrome

Chromosome 17q21.31 Microdeletion Syndrome

Monosomy 17q21.31

17q21.31 Deletion Syndrome

Koolen Syndrome

Del(17)(Q21.31)
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08717 MSL2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus MSL2 VGNC VGNC:63636
Rattus norvegicus MSL2 RGD RGD:1310355
Bos taurus MSL2 VGNC VGNC:31699
Mus musculus MSL2 MGD MGI:1925103
Macaca mulatta MSL2 VGNC VGNC:74827
Canis familiaris MSL2 VGNC VGNC:43444