2. Gene
  3. MACO1 - macoilin 1 Gene

MACO1 - macoilin 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as TMEM57; MACOILIN

Gene ID: 55219 | Gene type: protein coding

About MACO1

Cytogenetic location: 1p36.11 Genomic coordinates (GRCh38): 1:25,430,897-25,500,209 (from NCBI)

This gene has 4 transcripts (splice variants) and 286 orthologues. Ubiquitous expression in testis (RPKM 13.0), bone marrow (RPKM 10.8) and 25 other tissues.

Summary

Predicted to enable actin filament binding activity and microtubule binding activity. Involved in neuronal signal transduction. Located in rough endoplasmic reticulum membrane. [provided by Alliance of Genome Resources, Apr 2022]

MACO1 Products(2)

mRNA Protein Name
NM_001282564.2 NP_001269493.1 macoilin isoform b
NM_018202.6 NP_060672.2 macoilin isoform a

MACO1 Protein Structure

Macoilin

Macoilin: Macoilin family (2 - 662)

  • 0
  • 200
  • 400
  • 600
  • 664 a.a.
Protein Preferred Names Protein Names

macoilin

transmembrane protein 57

Related Diseases

Diseases Alias
Mitochondrial Complex Iii Deficiency

Complex 3 Mitochondrial Respiratory Chain Deficiency

Isolated Coq-Cytochrome C Reductase Deficiency

Ubiquinone-Cytochrome C Oxidoreductase Deficiency
Alkhurma Hemorrhagic Fever

Alkhumra Haemorrhagic Fever
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07944 MACO1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta MACO1 VGNC VGNC:100007
Felis catus MACO1 VGNC VGNC:63359
Mus musculus MACO1 MGD MGI:1913396
Bos taurus MACO1 VGNC VGNC:36098
Canis familiaris MACO1 VGNC VGNC:47589
Rattus norvegicus MACO1 RGD RGD:1561685