GIMAP4 - GTPase, IMAP family member 4 Gene

Homo sapiens

Also known as IAN1; IAN-1; IMAP4; MSTP062

Gene ID: 55303 | Gene type: protein coding

About GIMAP4

Cytogenetic location: 7q36.1 Genomic coordinates (GRCh38): 7:150,567,390-150,573,953 (from NCBI)

This gene has 5 transcripts (splice variants), 132 orthologues and 7 paralogues. Broad expression in lymph node (RPKM 64.9), spleen (RPKM 59.9) and 22 other tissues.

Summary

This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. The encoded protein of this gene may be negatively regulated by T-cell acute lymphocytic leukemia 1 (TAL1). In humans, the IAN subfamily genes are located in a cluster at 7q36.1. [provided by RefSeq, Jul 2008]

GIMAP4 Products(2)

mRNA	Protein	Name
NM_001363532.2	NP_001350461.1	GTPase IMAP family member 4 isoform 2
NM_018326.3	NP_060796.1	GTPase IMAP family member 4 isoform 1

GIMAP4 Protein Structure

AIG1

0
100
200
300
329 a.a.

Protein Preferred Names

Protein Names

GTPase IMAP family member 4

human immune associated nucleotide 1

Related Diseases

Diseases

Alias

Retinitis Pigmentosa 19

RP19	Retinitis Pigmentosa-19
Retinitis Pigmentosa, Type 19

Behcet Syndrome

Behcet Disease	Behcet'S Syndrome
Behcet'S Disease	Behçet Disease
Bd	Adamantiades-Behcet Disease
Triple Symptom Complex	Behçet'S Disease
Behet'S Syndrome	Bd Syndrome
Behçet Syndrome	Behçet'S Syndrome
Behcet Triple Symptom Complex	Malignant Aphthosis
Old Silk Route Disease	Adamantiades-Behçet Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05424	GIMAP4 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	GIMAP4	VGNC	VGNC:41217
Rattus norvegicus	GIMAP4	RGD	RGD:628765
Mus musculus	GIMAP4	MGD	MGI:1349656
Macaca mulatta	GIMAP4	VGNC	VGNC:72982

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