2. Gene
  3. CHRNA9 - cholinergic receptor nicotinic alpha 9 subunit Gene

CHRNA9 - cholinergic receptor nicotinic alpha 9 subunit Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as NACHRA9; HSA243342

Gene ID: 55584 | Gene type: protein coding

About CHRNA9

Cytogenetic location: 4p14 Genomic coordinates (GRCh38): 4:40,335,333-40,355,217 (from NCBI)

This gene has 3 transcripts (splice variants), 260 orthologues and 45 paralogues. Low expression observed in reference dataset.

Summary

This gene is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea. [provided by RefSeq, Feb 2012]

CHRNA9 Products(1)

mRNA Protein Name
NM_017581.4 NP_060051.2 neuronal acetylcholine receptor subunit alpha-9 precursor

CHRNA9 Protein Structure

Neur_chan_LBD

Neur_chan_LBD: Neurotransmitter-gated ion-channel ligand binding domain (32 - 236)

Neur_chan_memb

Neur_chan_memb: Neurotransmitter-gated ion-channel transmembrane region (244 - 474)

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  • 479 a.a.
Protein Preferred Names Protein Names

neuronal acetylcholine receptor subunit alpha-9

NACHR alpha 9

Related Diseases

Diseases Alias
Tobacco Addiction

Nicotine Dependence

Tobacco Addiction, Susceptibility To

Nicotine Addiction

Tobacco Use Disorder

Smoking Habit

Nicotine Dependence, Protection Against

Nicotine Addiction, Protection From

Cigarette Habituation

Cigarette Habituation, Susceptibility To

Smoking Habit, Susceptibility To

Nicotine Dependence, Susceptibility To

Nicotine Addiction, Susceptibility To

Addiction, Tobacco, Susceptibility To

Compulsive Tobacco User Syndrome

Tobacco Dependence

Tobacco Dependence Syndrome

Cigarette Addiction

Cigarette Dependence

Smoking Addiction

Smokers Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02673 CHRNA9 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CHRNA9 VGNC VGNC:27329
Canis familiaris CHRNA9 VGNC VGNC:39241
Felis catus CHRNA9 VGNC VGNC:78469
Macaca mulatta CHRNA9 VGNC VGNC:70947
Rattus norvegicus CHRNA9 RGD RGD:621534
Mus musculus CHRNA9 MGD MGI:1202403