2. Gene
  3. MINDY1 - MINDY lysine 48 deubiquitinase 1 Gene

MINDY1 - MINDY lysine 48 deubiquitinase 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as FAM63A; MINDY-1

Gene ID: 55793 | Gene type: protein coding

About MINDY1

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:150,996,536-151,008,393 (from NCBI)

This gene has 7 transcripts (splice variants), 207 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 17.7), testis (RPKM 8.4) and 25 other tissues.

Summary

Enables K48-linked polyubiquitin modification-dependent protein binding activity; Lys48-specific Deubiquitinase activity; and cysteine-type Carboxypeptidase activity. Predicted to be involved in protein K48-linked deubiquitination. Located in nuclear body. [provided by Alliance of Genome Resources, Apr 2022]

MINDY1 Products(17)

mRNA Protein Name
NM_001040217.3 NP_001035307.2 ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform 2
NM_001163258.3 NP_001156730.3 ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform 1
NM_001163259.2 NP_001156731.2 ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform 4
NM_001163260.2 NP_001156732.2 ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform 2
NM_001319998.2 NP_001306927.2 ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform 1
NM_001376664.1 NP_001363593.1 ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform 5
NM_001376665.1 NP_001363594.1 ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform 1
NM_001376666.1 NP_001363595.1 ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform 7
NM_001376667.1 NP_001363596.1 ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform 8
NM_001376668.1 NP_001363597.1 ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform 8
NM_001376669.1 NP_001363598.1 ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform 9
NM_001376670.1 NP_001363599.1 ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform 10
NM_001376671.1 NP_001363600.1 ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform 11
NM_001376672.1 NP_001363601.1 ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform 12
NM_001376673.1 NP_001363602.1 ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform 12
NM_001376674.1 NP_001363603.1 ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform 13
NM_018379.5 NP_060849.3 ubiquitin carboxyl-terminal hydrolase MINDY-1 isoform 1

MINDY1 Protein Structure

MINDY_DUB

MINDY_DUB: MINDY deubiquitinase (143 - 268)

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  • 469 a.a.
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase MINDY-1

MINDY deubiquitinase 1

Related Diseases

Diseases Alias
Nipah Virus Encephalitis

Equine Morbillivirus
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08451 MINDY1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus MINDY1 VGNC VGNC:63510
Bos taurus MINDY1 VGNC VGNC:55615
Mus musculus MINDY1 MGD MGI:1922257
Canis familiaris MINDY1 VGNC VGNC:43236
Macaca mulatta MINDY1 VGNC VGNC:74828
Rattus norvegicus MINDY1 RGD RGD:1559660