FOXJ2 - forkhead box J2 Gene

Homo sapiens

Also known as FHX

Gene ID: 55810 | Gene type: protein coding

About FOXJ2

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:8,032,716-8,055,517 (from NCBI)

This gene has 3 transcripts (splice variants), 124 orthologues and 42 paralogues. Ubiquitous expression in endometrium (RPKM 8.4), ovary (RPKM 8.2) and 25 other tissues.

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Involved in several processes, including negative regulation of angiogenesis; negative regulation of blood vessel endothelial cell differentiation; and positive regulation of vascular associated smooth muscle cell proliferation. Located in fibrillar center and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

FOXJ2 Products(1)

mRNA	Protein	Name
NM_018416.3	NP_060886.1	forkhead box protein J2

FOXJ2 Protein Structure

Forkhead

0
100
200
300
400
500
574 a.a.

Protein Preferred Names

Protein Names

forkhead box protein J2

FOXJ2 forkhead factor

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05057	FOXJ2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	FOXJ2	VGNC	VGNC:62337
Macaca mulatta	FOXJ2	VGNC	VGNC:72568
Bos taurus	FOXJ2	VGNC	VGNC:29090
Rattus norvegicus	FOXJ2	RGD	RGD:1565101
Canis familiaris	FOXJ2	VGNC	VGNC:40955
Mus musculus	FOXJ2	MGD	MGI:1926805

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