PCDHB6 - protocadherin beta 6 Gene

Homo sapiens

Also known as PCDH-BETA6

Gene ID: 56130 | Gene type: protein coding

About PCDHB6

Cytogenetic location: 5q31.3 Genomic coordinates (GRCh38): 5:141,150,057-141,153,287 (from NCBI)

This gene has 2 transcripts (splice variants), 53 orthologues and 61 paralogues.

Summary

This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. Unlike the alpha and gamma clusters, the transcripts from these genes do not share common 3' exons. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell neural connections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

PCDHB6 Products(2)

mRNA	Protein	Name
NM_001303145.2	NP_001290074.1	protocadherin beta-6 isoform 2
NM_018939.4	NP_061762.2	protocadherin beta-6 isoform 1 precursor

PCDHB6 Protein Structure

Cadherin_2

Cadherin

0
200
400
600
794 a.a.

Protein Preferred Names

Protein Names

protocadherin beta-6

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10139	PCDHB6 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	PCDHB6	MGD	MGI:2136748
Rattus norvegicus	PCDHB6	RGD	RGD:11376545

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