2. Gene
  3. GPR137 - G protein-coupled receptor 137 Gene

GPR137 - G protein-coupled receptor 137 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as C11orf4; GPR137A; TM7SF1L1

Gene ID: 56834 | Gene type: protein coding

About GPR137

This gene has 19 transcripts (splice variants), 175 orthologues and 2 paralogues. Broad expression in testis (RPKM 30.3), brain (RPKM 9.0) and 24 other tissues.

Summary

Predicted to be involved in several processes, including negative regulation of bone resorption; negative regulation of osteoclast differentiation; and positive regulation of TORC1 signaling. Located in lysosomal membrane. [provided by Alliance of Genome Resources, Apr 2022]

GPR137 Products(18)

mRNA Protein Name
NM_001170880.2 NP_001164351.1 integral membrane protein GPR137 isoform 2
NM_001170881.2 NP_001164352.1 integral membrane protein GPR137 isoform 1
NM_001177358.2 NP_001170829.1 integral membrane protein GPR137 isoform 5
NM_001378076.1 NP_001365005.1 integral membrane protein GPR137 isoform 1
NM_001378077.1 NP_001365006.1 integral membrane protein GPR137 isoform 1
NM_001378078.1 NP_001365007.1 integral membrane protein GPR137 isoform 2
NM_001378079.1 NP_001365008.1 integral membrane protein GPR137 isoform 2
NM_001378080.1 NP_001365009.1 integral membrane protein GPR137 isoform 2
NM_001378081.1 NP_001365010.1 integral membrane protein GPR137 isoform 2
NM_001378082.1 NP_001365011.1 integral membrane protein GPR137 isoform 2
NM_001378083.1 NP_001365012.1 integral membrane protein GPR137 isoform 3
NM_001378084.1 NP_001365013.1 integral membrane protein GPR137 isoform 5
NM_001378085.1 NP_001365014.1 integral membrane protein GPR137 isoform 5
NM_001378086.1 NP_001365015.1 integral membrane protein GPR137 isoform 5
NM_001378087.1 NP_001365016.1 integral membrane protein GPR137 isoform 6
NM_001378088.1 NP_001365017.1 integral membrane protein GPR137 isoform 6
NM_001378089.1 NP_001365018.1 integral membrane protein GPR137 isoform 7
NM_020155.4 NP_064540.3 integral membrane protein GPR137 isoform 3
Protein Preferred Names Protein Names

integral membrane protein GPR137

transmembrane 7 superfamily member 1-like 1 protein

Related Diseases

Diseases Alias
Retinitis Pigmentosa 60

RP60

Retinitis Pigmentosa, Type 60
Isolated Growth Hormone Deficiency, Type Ib

Isolated Growth Hormone Deficiency Type Ib

IGHD1B

Ighd Ib

Growth Hormone Deficiency, Isolated, Type Ib

Congenital Ighd Type Ib

Congenital Isolated Gh Deficiency Type Ib

Congenital Isolated Growth Hormone Deficiency Type Ib

Dwarfism Of Sindh

Pituitary Dwarfism I

Isolated Growth Hormone Deficiency Type 1b

Ighd 1b

Growth Hormone Deficiency, Isolated, 1b
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05658 GPR137 Human Pre-designed siRNA Set A / Unkown
HY-RS05659 GPR137B Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus GPR137 MGD MGI:2147529
Macaca mulatta GPR137 VGNC VGNC:72994
Bos taurus GPR137 VGNC VGNC:29550
Canis familiaris GPR137 VGNC VGNC:41397
Rattus norvegicus GPR137 RGD RGD:1586317