EMC7 - ER membrane protein complex subunit 7 Gene

Homo sapiens

Also known as HT022; C11orf3; C15orf24; ORF1-FL1

Gene ID: 56851 | Gene type: protein coding

About EMC7

This gene has 4 transcripts (splice variants) and 208 orthologues. Ubiquitous expression in testis (RPKM 46.7), adrenal (RPKM 45.9) and 25 other tissues.

Summary

Contributes to membrane insertase activity. Involved in protein insertion into ER membrane by stop-transfer membrane-anchor sequence and tail-anchored membrane protein insertion into ER membrane. Is integral component of endoplasmic reticulum membrane. Part of EMC complex. [provided by Alliance of Genome Resources, Apr 2022]

EMC7 Products(1)

mRNA	Protein	Name
NM_020154.3	NP_064539.1	ER membrane protein complex subunit 7 precursor

EMC7 Protein Structure

DUF2012

0
100
200
242 a.a.

Protein Preferred Names

Protein Names

ER membrane protein complex subunit 7

UPF0480 protein C15orf24

Related Diseases

Diseases

Alias

Nodular Hidradenoma

Eccrine Nodular Hidradenoma

Eccrine Acrospiroma

Acrospiroma	Poroma
Eccrine Hidradenoma	Eccrine Hidradenoma Of Skin
Hidradenoma	Adenoma, Sweat Gland
Benign Neoplasm Of Sweat Gland	Eccrine Poroma

Eccrine Sweat Gland Neoplasm

Eccrine Skin Neoplasm	Eccrine Tumor
Eccrine Neoplasm	Malignant Eccrine Neoplasm

Hidradenoma

Adenoma, Sweat Gland	Hidradenoma Of Skin
Sweat Gland Adenoma	Syringoadenoma
Eccrine Acrospiroma	Benign Neoplasm Of Sweat Gland

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04341	EMC7 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	EMC7	MGD	MGI:1920274
Canis familiaris	EMC7	VGNC	VGNC:40336
Bos taurus	EMC7	VGNC	VGNC:55112
Rattus norvegicus	EMC7	RGD	RGD:1305045
Felis catus	EMC7	VGNC	VGNC:61837
Macaca mulatta	EMC7	VGNC	VGNC:72094

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