LPAR5 - lysophosphatidic acid receptor 5 Gene

Homo sapiens

Also known as LPA5; GPR92; GPR93; KPG_010

Gene ID: 57121 | Gene type: protein coding

About LPAR5

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:6,618,835-6,635,959 (from NCBI)

This gene has 3 transcripts (splice variants), 252 orthologues and 1 paralogue. Broad expression in colon (RPKM 5.6), lymph node (RPKM 4.4) and 23 other tissues.

Summary

This gene encodes a member of the rhodopsin class of G protein-coupled transmembrane receptors. This protein transmits extracellular signals from lysophosphatidic acid to cells through heterotrimeric G proteins and mediates numerous cellular processes. Many G protein receptors serve as targets for pharmaceutical drugs. Transcript variants of this gene have been described.[provided by RefSeq, Dec 2008]

LPAR5 Products(2)

mRNA	Protein	Name
NM_020400.6	NP_065133.1	lysophosphatidic acid receptor 5
NM_001142961.1	NP_001136433.1	lysophosphatidic acid receptor 5

LPAR5 Protein Structure

7tm_1

0
100
200
300
372 a.a.

Protein Preferred Names

Protein Names

lysophosphatidic acid receptor 5

G protein-coupled receptor 92	G-protein coupled receptor 93
LPA receptor 5	LPA-5

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-15706	H2L 5765834	Antagonist	98.36%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	LPAR5	RGD	RGD:1562580
Macaca mulatta	LPAR5	VGNC	VGNC:74277
Canis familiaris	LPAR5	VGNC	VGNC:42746
Felis catus	LPAR5	VGNC	VGNC:82321
Mus musculus	LPAR5	MGD	MGI:2685918
Bos taurus	LPAR5	VGNC	VGNC:30959