MRS2 - magnesium transporter MRS2 Gene

Homo sapiens

Also known as HPT; MRS2L

Gene ID: 57380 | Gene type: protein coding

About MRS2

Cytogenetic location: 6p22.3 Genomic coordinates (GRCh38): 6:24,402,936-24,426,190 (from NCBI)

This gene has 6 transcripts (splice variants) and 200 orthologues. Ubiquitous expression in heart (RPKM 8.7), thyroid (RPKM 7.9) and 25 other tissues.

Summary

Enables magnesium ion transmembrane transporter activity. Involved in mitochondrial magnesium ion transmembrane transport. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

MRS2 Products(4)

mRNA	Protein	Name
NM_001286264.2	NP_001273193.1	magnesium transporter MRS2 homolog, mitochondrial isoform a
NM_001286265.2	NP_001273194.1	magnesium transporter MRS2 homolog, mitochondrial isoform c
NM_001286266.2	NP_001273195.1	magnesium transporter MRS2 homolog, mitochondrial isoform d
NM_020662.4	NP_065713.1	magnesium transporter MRS2 homolog, mitochondrial isoform b precursor

Protein Preferred Names

Protein Names

magnesium transporter MRS2 homolog, mitochondrial

MRS2, magnesium transporter

Related Diseases

Diseases

Alias

Middle Cerebral Artery Infarction

Infarction, Middle Cerebral Artery

Infarction Middle Cerebral Artery

Basilar Artery Occlusion

Phlebotomus Fever

Pappataci Fever	Sandfly Fever
Sandfly-Borne Phleboviral Disease	Sandfly-Borne Arboviral Fever
Sandfly-Borne Bunyavirus Fever	Three Day Fever
Chitral Fever	Italy Summer Grippe
Italy Summer Grippe Influenza

Robinow Syndrome, Autosomal Dominant 2

Autosomal Dominant Robinow Syndrome 2	DRS2
Robinow, Autosomal Dominant Syndrome, Type 2

Vertebral Artery Occlusion

Occlusion And Stenosis Of Vertebral Artery

Ivic Syndrome

Oculootoradial Syndrome	Radial Ray Defects, Hearing Impairment, External Ophthalmoplegia, And Thrombocytopenia
IVIC	Instituto Venezolano De Investigaciones Cientificas Syndrome
Oculo-Oto-Radial Syndrome	Oors

Subdural Empyema

Empyema, Subdural

Subdural Abscess

Robinow Syndrome, Autosomal Dominant 1

Autosomal Dominant Robinow Syndrome 1	DRS1
Robinow Dwarfism	Fetal Face Syndrome
Acral Dysostosis With Facial And Genital Abnormalities	Robinow, Autosomal Dominant Syndrome, Type 1

Cerebral Arterial Disease

Cerebral Arterial Diseases

Intracranial Berry Aneurysm

Familial Aneurysmal Subarachnoid Hemorrhage	Familial Berry Aneurysm
Familial Intracranial Saccular Aneurysm	Saccular Cerebral Aneurysm
Aneurysm, Intracranial Berry	Aneurysmal Subarachnoid Hemorrhage
Aneurysm, Intracranial Berry, 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08692	MRS2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	MRS2	VGNC	VGNC:63627
Rattus norvegicus	MRS2	RGD	RGD:708529
Canis familiaris	MRS2	VGNC	VGNC:43429
Macaca mulatta	MRS2	VGNC	VGNC:74735
Bos taurus	MRS2	VGNC	VGNC:31679
Mus musculus	MRS2	MGD	MGI:2685748