2. Gene
  3. RHOJ - ras homolog family member J Gene

RHOJ - ras homolog family member J Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as TCL; ARHJ; TC10B; RASL7B

Gene ID: 57381 | Gene type: protein coding

About RHOJ

Cytogenetic location: 14q23.2 Genomic coordinates (GRCh38): 14:63,204,443-63,293,508 (from NCBI)

This gene has 4 transcripts (splice variants), 149 orthologues and 22 paralogues. Ubiquitous expression in gall bladder (RPKM 9.9), lung (RPKM 9.2) and 23 other tissues.

Summary

This gene encodes one of the many small GTP-binding proteins in the Rho family shown to be associated with focal adhesions in endothelial cells (PMID: 21148427, 22103495). The encoded protein is activated by vascular endothelial growth factor and may regulate angiogenesis. [provided by RefSeq, Dec 2011]

RHOJ Products(1)

mRNA Protein Name
NM_020663.5 NP_065714.1 rho-related GTP-binding protein RhoJ

RHOJ Protein Structure

Ras

Ras: Ras family (23 - 194)

  • 0
  • 100
  • 200
  • 214 a.a.
Protein Preferred Names Protein Names

rho-related GTP-binding protein RhoJ

RAS-like, family 7, member B

Related Diseases

Diseases Alias
Parasitic Ichthyosporea Infectious Disease
Rhinosporidiosis

Infection By Rhinosporidium Seeberi

Rhinosporosis
Macular Dystrophy, Patterned, 3

Martinique Crinkled Retinal Pigment Epitheliopathy

Patterned Macular Dystrophy 3

MDPT3

Mcrpe
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11955 RHOJ Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta RHOJ VGNC VGNC:76885
Felis catus RHOJ VGNC VGNC:80867
Bos taurus RHOJ VGNC VGNC:33951
Canis familiaris RHOJ VGNC VGNC:45562
Rattus norvegicus RHOJ RGD RGD:1310528
Mus musculus RHOJ MGD MGI:1931551