2. Gene
  3. LRFN2 - leucine rich repeat and fibronectin type III domain containing 2 Gene

LRFN2 - leucine rich repeat and fibronectin type III domain containing 2 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as SALM1; FIGLER2; KIAA1246

Gene ID: 57497 | Gene type: protein coding

About LRFN2

Cytogenetic location: 6p21.2-p21.1 Genomic coordinates (GRCh38): 6:40,391,591-40,587,364 (from NCBI)

This gene has 2 transcripts (splice variants), 260 orthologues and 25 paralogues. Low expression observed in reference dataset.

Summary

Predicted to be involved in modulation of chemical synaptic transmission and regulation of postsynapse organization. Predicted to be located in plasma membrane. Predicted to be active in Schaffer collateral - CA1 synapse and cell surface. Predicted to be integral component of postsynaptic density membrane. [provided by Alliance of Genome Resources, Apr 2022]

LRFN2 Products(1)

mRNA Protein Name
NM_020737.3 NP_065788.1 leucine-rich repeat and fibronectin type-III domain-containing protein 2 precursor

LRFN2 Protein Structure

LRR_8

LRR_8: Leucine rich repeat (56 - 112)

LRR_8

LRR_8: Leucine rich repeat (151 - 209)

I-set

I-set: Immunoglobulin I-set domain (290 - 376)

fn3

fn3: Fibronectin type III domain (420 - 494)

  • 0
  • 200
  • 400
  • 600
  • 789 a.a.
Protein Preferred Names Protein Names

leucine-rich repeat and fibronectin type-III domain-containing protein 2

fibronectin type III, immunoglobulin and leucine rich repeat domains 2

Related Diseases

Diseases Alias
Neuronitis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07782 LRFN2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus LRFN2 VGNC VGNC:30976
Canis familiaris LRFN2 VGNC VGNC:42761
Mus musculus LRFN2 MGD MGI:1917780
Felis catus LRFN2 VGNC VGNC:63275
Macaca mulatta LRFN2 VGNC VGNC:74328
Rattus norvegicus LRFN2 RGD RGD:1311831