CGN - cingulin Gene

Homo sapiens

Gene ID: 57530 | Gene type: protein coding

About CGN

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:151,510,170-151,538,692 (from NCBI)

This gene has 8 transcripts (splice variants), 171 orthologues and 43 paralogues. Broad expression in small intestine (RPKM 30.7), duodenum (RPKM 28.7) and 15 other tissues.

Summary

Enables cadherin binding activity. Predicted to act upstream of or within bicellular tight junction assembly; epithelial cell morphogenesis; and microtubule Cytoskeleton organization. Located in bicellular tight junction and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

CGN Products(1)

mRNA	Protein	Name
NM_020770.3	NP_065821.1	cingulin

CGN Protein Structure

Myosin_tail_1

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1203 a.a.

Protein Preferred Names

Protein Names

cingulin

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-111793A	NUCC-390 dihydrochloride	Agonist	99.05%	Unkown
HY-111793	NUCC-390	Agonist	/	Unkown
HY-RS02585	CGN Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	CGN	MGD	MGI:1927237
Macaca mulatta	CGN	VGNC	VGNC:70968
Felis catus	CGN	VGNC	VGNC:80168
Bos taurus	CGN	VGNC	VGNC:27258
Rattus norvegicus	CGN	RGD	RGD:1311992
Canis familiaris	CGN	VGNC	VGNC:39183
Others	CGN	NCBI

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