2. Gene
  3. REG1B - regenerating family member 1 beta Gene

REG1B - regenerating family member 1 beta Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as REGH; REGL; PSPS2; REGI-BETA

Gene ID: 5968 | Gene type: protein coding

About REG1B

Cytogenetic location: 2p12 Genomic coordinates (GRCh38): 2:79,085,023-79,087,993 (from NCBI)

This gene has 5 transcripts (splice variants), 934 orthologues and 5 paralogues. Biased expression in duodenum (RPKM 280.8), small intestine (RPKM 149.9) and 2 other tissues.

Summary

This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV based on the primary structures of the encoded proteins. This gene encodes a protein secreted by the exocrine pancreas that is highly similar to the REG1A protein. The related REG1A protein is associated with islet cell regeneration and diabetogenesis, and may be involved in pancreatic lithogenesis. Reg family members REG1A, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication. [provided by RefSeq, Jul 2008]

REG1B Products(1)

mRNA Protein Name
NM_006507.4 NP_006498.1 lithostathine-1-beta precursor

REG1B Protein Structure

Lectin_C

Lectin_C: Lectin C-type domain (54 - 163)

  • 0
  • 100
  • 166 a.a.
Protein Preferred Names Protein Names

lithostathine-1-beta

PSP-2

Recombinant REG1B Proteins

Cat. No. Product Name Accession Purity
HY-P76565 REG-1 beta/REG1B Protein, Human (HEK293, His) P48304 (Q23-N166) ≥95%

Related Diseases

Diseases Alias
Pancreatitis

Mumps Pancreatitis
Anaerobic Pneumonia

Pneumonia Due To Anaerobes
Amebiasis

Amoebiasis

Entamoebiasis

Chronic Intestinal Amebiasis

Amoebiasis, Unspecified

Amebic Colitis

Amoebic Enteritis

Infection Due To Entamoeba Histolytica

Amoebic Infection

Disease Due To Endamoebidae

Amoebiasis Nos
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11819 REG1B Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta REG1B NCBI
Others REG1B NCBI