MYG1 - MYG1 exonuclease Gene

Homo sapiens

Also known as MYG; Gamm1; MST024; MSTP024; C12orf10

Gene ID: 60314 | Gene type: protein coding

About MYG1

Cytogenetic location: 12q13.13 Genomic coordinates (GRCh38): 12:53,299,695-53,307,177 (from NCBI)

This gene has 10 transcripts (splice variants) and 204 orthologues. Broad expression in testis (RPKM 46.7), ovary (RPKM 22.5) and 25 other tissues.

Summary

Predicted to enable nuclease activity. Predicted to be involved in nucleic acid phosphodiester bond hydrolysis. Predicted to act upstream of or within locomotory exploration behavior. Located in mitochondrion and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

MYG1 Products(1)

mRNA	Protein	Name
NM_021640.4	NP_067653.4	MYG1 exonuclease precursor

MYG1 Protein Structure

UPF0160

0
100
200
300
376 a.a.

Protein Preferred Names

Protein Names

MYG1 exonuclease

UPF0160 protein MYG1, mitochondrial

Related Diseases

Diseases

Alias

Nemaline Myopathy 4

Cap Myopathy 2	NEM4
Nemaline Myopathy 4, Autosomal Dominant	Nemaline Myopathy, Type 4
CAPM2	Cap Disease
Cap Myopathy Tpm2-Related	Tpm2-Related Nemaline Myopathy
Tpm2-Related Cap Myopathy	Myopathy, Nemaline, Type 4
Cap Myopathy

Dracunculiasis

Guinea Worm Disease	Dracontiasis
Dracunculosis	Infection By Dracunculus Medinensis
Gwd	Guinea Worm Infection
Parasitic Infection Caused By Dracunculus Medinensis	Medina Worm Disease
Medinensis	Medina Worm Infestation
Dracunculus Medinensis Infestation	Guinea Worm Infestation

Vitiligo-Associated Multiple Autoimmune Disease Susceptibility 1

Vitiligo	VAMAS1
Slev1	Vtlg
Systemic Lupus Erythematosus, Vitiligo-Related	Vitiligo-Associated Multiple Autoimmune Disease 1
Systemic Lupus Erythematosus Vitiligo-Related

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08894	MYG1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	MYG1	VGNC	VGNC:49228
Mus musculus	MYG1	MGD	MGI:1929864
Macaca mulatta	MYG1	VGNC	VGNC:70338
Bos taurus	MYG1	VGNC	VGNC:49159
Rattus norvegicus	MYG1	RGD	RGD:1359237

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