1. Gene
  2. RPL13 - ribosomal protein L13 Gene

RPL13 - ribosomal protein L13 Gene

Homo sapiens

Also known as L13; BBC1; D16S44E; SEMDIST; D16S444E

Gene ID: 6137 | Gene type: protein coding

About RPL13

Cytogenetic location: 16q24.3 Genomic coordinates (GRCh38): 16:89,560,657-89,566,829 (from NCBI)

This gene has 15 transcripts (splice variants), 244 orthologues and is associated with 2 phenotypes. Ubiquitous expression in ovary (RPKM 234.6), spleen (RPKM 109.8) and 25 other tissues.

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L13E family of ribosomal proteins. It is located in the cytoplasm. This gene is expressed at significantly higher levels in benign breast lesions than in breast carcinomas. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2011]

RPL13 Products(3)

mRNA Protein Name
NM_000977.4 NP_000968.2 60S ribosomal protein L13 isoform 1
NM_001243131.1 NP_001230060.1 60S ribosomal protein L13 isoform 3
NM_033251.2 NP_150254.1 60S ribosomal protein L13 isoform 1

RPL13 Protein Structure

Ribosomal_L13e

Ribosomal_L13e: Ribosomal protein L13e (8 - 185)

  • 0
  • 100
  • 211 a.a.
Protein Preferred Names Protein Names

60S ribosomal protein L13

breast basic conserved 1

Related Diseases

Diseases Alias
Spondyloepimetaphyseal Dysplasia, Isidor-Toutain Type

SEMDIST

Spondyloepimetaphyseal Dysplasia

Dysplasia, Spondyloepimetaphyseal

Myeloid And Lymphoid Neoplasms Associated With Fgfr1 Abnormalities
Postcholecystectomy Syndrome

Post Cholecystectomy Syndrome

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus RPL13 VGNC VGNC:34109
Rattus norvegicus RPL13 RGD RGD:621179
Canis familiaris RPL13 VGNC VGNC:53438
Felis catus RPL13 VGNC VGNC:103746
Macaca mulatta RPL13 VGNC VGNC:82227
Mus musculus RPL13 MGD MGI:105922