2. Gene
  3. RPL17 - ribosomal protein L17 Gene

RPL17 - ribosomal protein L17 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as L17; PD-1; RPL23

Gene ID: 6139 | Gene type: protein coding

About RPL17

Cytogenetic location: 18q21.1 Genomic coordinates (GRCh38): 18:49,488,481-49,492,465 (from NCBI)

This gene has 24 transcripts (splice variants) and 89 orthologues. Ubiquitous expression in ovary (RPKM 688.1), bone marrow (RPKM 341.0) and 25 other tissues.

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22P family of ribosomal proteins. It is located in the cytoplasm. This gene has been referred to as rpL23 because the encoded protein shares amino acid identity with ribosomal protein L23 from Halobacterium marismortui; however, its official symbol is RPL17. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream C18orf32 (chromosome 18 open reading frame 32) gene. [provided by RefSeq, Dec 2010]

RPL17 Products(16)

mRNA Protein Name
NM_000985.5 NP_000976.1 60S ribosomal protein L17 isoform a
NM_001035006.5 NP_001030178.1 60S ribosomal protein L17 isoform a
NM_001199340.2 NP_001186269.1 60S ribosomal protein L17 isoform a
NM_001199341.3 NP_001186270.1 60S ribosomal protein L17 isoform a
NM_001199342.3 NP_001186271.1 60S ribosomal protein L17 isoform a
NM_001199343.3 NP_001186272.1 60S ribosomal protein L17 isoform a
NM_001199344.3 NP_001186273.1 60S ribosomal protein L17 isoform a
NM_001199345.2 NP_001186274.1 60S ribosomal protein L17 isoform b
NM_001369555.1 NP_001356484.1 60S ribosomal protein L17 isoform c
NM_001369556.1 NP_001356485.1 60S ribosomal protein L17 isoform a
NM_001369557.1 NP_001356486.1 60S ribosomal protein L17 isoform a
NM_001369558.1 NP_001356487.1 60S ribosomal protein L17 isoform a
NM_001369560.1 NP_001356489.1 60S ribosomal protein L17 isoform d
NM_001369561.1 NP_001356490.1 60S ribosomal protein L17 isoform d
NM_001369562.1 NP_001356491.1 60S ribosomal protein L17 isoform b
NM_001369563.1 NP_001356492.1 60S ribosomal protein L17 isoform b

RPL17 Protein Structure

Ribosomal_L22

Ribosomal_L22: Ribosomal protein L22p/L17e (19 - 152)

  • 0
  • 100
  • 184 a.a.
Protein Preferred Names Protein Names

60S ribosomal protein L17

60S ribosomal protein L23

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12168 RPL17 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus RPL17 RGD RGD:1303019
Mus musculus RPL17 MGD MGI:2448270