RPL19 - ribosomal protein L19 Gene

Homo sapiens

Also known as L19

Gene ID: 6143 | Gene type: protein coding

About RPL19

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:39,200,283-39,204,732 (from NCBI)

This gene has 13 transcripts (splice variants) and 240 orthologues. Ubiquitous expression in ovary (RPKM 933.9), lymph node (RPKM 615.1) and 25 other tissues.

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L19E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

RPL19 Products(2)

mRNA	Protein	Name
NM_000981.4	NP_000972.1	60S ribosomal protein L19 isoform 1
NM_001330200.1	NP_001317129.1	60S ribosomal protein L19 isoform 2

RPL19 Protein Structure

Ribosomal_L19e

0
100
196 a.a.

Protein Preferred Names

Protein Names

60S ribosomal protein L19

large ribosomal subunit protein eL19

Related Diseases

Diseases

Alias

Psoriasis 13

PSORS13	Psoriasis 13, Susceptibility To
Psoriasis	Psoriasis Vulgaris
Psoriasis Susceptibility 13	Pv
Psoriasis, Susceptibility To, Type 13

Diamond-Blackfan Anemia

Congenital Pure Red Cell Aplasia	Aase Syndrome
Erythrogenesis Imperfecta	Anemia, Diamond-Blackfan
Congenital Hypoplastic Anemia	Aase-Smith Ii Syndrome
Bds	Blackfan-Diamond Anemia
Congenital Prca	Congenital Hypoplastic Anemia, Blackfan-Diamond Type
Dba	Blackfan - Diamond Syndrome
Chronic Constitutional Pure Red Cell Anaemia	Anemia Diamond Blackfan Type
Anemia Congenital Erythroid Hypoplastic	Aregenerative Anemia Chronic Congenital
Blackfan Diamond Syndrome	Red Cell Aplasia, Pure Hereditary
Aase-Smith Syndrome Ii	Bda
Blackfan Diamond Anemia	Blackfan-Diamond Disease
Blackfan-Diamond Syndrome	Chronic Congenital Agenerative Anemia
Congenital Erythroid Hypoplastic Anemia	Congenital Hypoplastic Anemia Of Blackfan And Diamond
Congenital Pure Red Cell Anemia	Hypoplastic Congenital Anemia
Inherited Erythroblastopenia	Pure Hereditary Red Cell Aplasia
Anemia, Hypoplastic, Congenital	Anemia Hypoplastic Congenital
Fanconi Anemia	Constitutional Aplastic Anemia
Diamond-Blackfan Anemia 1	Aase Smith Syndrome 2
Congenital Red Cell Aplasia	Red Cell Aplasia Of Infants
Pure Red Cell Aplasia Of Infants	Congenital Red Cell Aplastic Anaemia
Congenital Pure Red Cell Anaemia	Congenital Erythroid Hypoplasia
Pearson Marrow-Pancreas Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12171	RPL19 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	RPL19	VGNC	VGNC:45715
Bos taurus	RPL19	VGNC	VGNC:49956
Mus musculus	RPL19	MGD	MGI:98020
Felis catus	RPL19	VGNC	VGNC:99436
Rattus norvegicus	RPL19	RGD	RGD:621183

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