RPL31 - ribosomal protein L31 Gene

Homo sapiens

Also known as L31

Gene ID: 6160 | Gene type: protein coding

About RPL31

Cytogenetic location: 2q11.2 Genomic coordinates (GRCh38): 2:101,002,289-101,019,724 (from NCBI)

This gene has 11 transcripts (splice variants), 157 orthologues and is associated with 1 phenotype. Ubiquitous expression in ovary (RPKM 450.2), bone marrow (RPKM 284.8) and 25 other tissues.

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L31E family of ribosomal proteins. It is located in the cytoplasm. Higher levels of expression of this gene in familial adenomatous polyps compared to matched normal tissues have been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

RPL31 Products(3)

mRNA	Protein	Name
NM_000993.5	NP_000984.1	60S ribosomal protein L31 isoform 1
NM_001098577.3	NP_001092047.1	60S ribosomal protein L31 isoform 2
NM_001099693.2	NP_001093163.1	60S ribosomal protein L31 isoform 3

RPL31 Protein Structure

Ribosomal_L31e

0
100
125 a.a.

Protein Preferred Names

Protein Names

60S ribosomal protein L31

large ribosomal subunit protein eL31

Related Diseases

Diseases

Alias

Diamond-Blackfan Anemia

Congenital Pure Red Cell Aplasia	Aase Syndrome
Erythrogenesis Imperfecta	Anemia, Diamond-Blackfan
Congenital Hypoplastic Anemia	Aase-Smith Ii Syndrome
Bds	Blackfan-Diamond Anemia
Congenital Prca	Congenital Hypoplastic Anemia, Blackfan-Diamond Type
Dba	Blackfan - Diamond Syndrome
Chronic Constitutional Pure Red Cell Anaemia	Anemia Diamond Blackfan Type
Anemia Congenital Erythroid Hypoplastic	Aregenerative Anemia Chronic Congenital
Blackfan Diamond Syndrome	Red Cell Aplasia, Pure Hereditary
Aase-Smith Syndrome Ii	Bda
Blackfan Diamond Anemia	Blackfan-Diamond Disease
Blackfan-Diamond Syndrome	Chronic Congenital Agenerative Anemia
Congenital Erythroid Hypoplastic Anemia	Congenital Hypoplastic Anemia Of Blackfan And Diamond
Congenital Pure Red Cell Anemia	Hypoplastic Congenital Anemia
Inherited Erythroblastopenia	Pure Hereditary Red Cell Aplasia
Anemia, Hypoplastic, Congenital	Anemia Hypoplastic Congenital
Fanconi Anemia	Constitutional Aplastic Anemia
Diamond-Blackfan Anemia 1	Aase Smith Syndrome 2
Congenital Red Cell Aplasia	Red Cell Aplasia Of Infants
Pure Red Cell Aplasia Of Infants	Congenital Red Cell Aplastic Anaemia
Congenital Pure Red Cell Anaemia	Congenital Erythroid Hypoplasia
Pearson Marrow-Pancreas Syndrome

Diamond-Blackfan Anemia 6

DBA6	Aase-Smith Syndrome Ii
Aase Syndrome	Aase Smith Syndrome 2
Rpl5-Related Diamond-Blackfan Anemia	Anemia, Diamond-Blackfan, Type 6
Diamond-Blackfan Anemia 1

Retinitis Pigmentosa 23

RP23	Retinitis Pigmentosa-23
Retinitis Pigmentosa, Type 23	Rp23 Gene

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12186	RPL31 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	RPL31	VGNC	VGNC:81212
Mus musculus	RPL31	MGD	MGI:2149632
Rattus norvegicus	RPL31	RGD	RGD:621202

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