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  3. RPL34 - ribosomal protein L34 Gene

RPL34 - ribosomal protein L34 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as L34

Gene ID: 6164 | Gene type: protein coding

About RPL34

Cytogenetic location: 4q25 Genomic coordinates (GRCh38): 4:108,620,576-108,630,484 (from NCBI)

This gene has 7 transcripts (splice variants) and 198 orthologues. Ubiquitous expression in ovary (RPKM 324.7), bone marrow (RPKM 227.1) and 25 other tissues.

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L34E family of ribosomal proteins. It is located in the cytoplasm. This gene originally was thought to be located at 17q21, but it has been mapped to 4q. Overexpression of this gene has been observed in some Cancer cells. Alternative splicing results in multiple transcript variants, all encoding the same isoform. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Feb 2016]

RPL34 Products(6)

mRNA Protein Name
NM_000995.5 NP_000986.2 60S ribosomal protein L34
NM_001319232.2 NP_001306161.1 60S ribosomal protein L34
NM_001319234.1 NP_001306163.1 60S ribosomal protein L34
NM_001319235.2 NP_001306164.1 60S ribosomal protein L34
NM_001319236.2 NP_001306165.1 60S ribosomal protein L34
NM_033625.4 NP_296374.1 60S ribosomal protein L34

RPL34 Protein Structure

Ribosomal_L34e

Ribosomal_L34e: Ribosomal protein L34e (1 - 96)

  • 0
  • 100
  • 117 a.a.
Protein Preferred Names Protein Names

60S ribosomal protein L34

large ribosomal subunit protein eL34

Related Diseases

Diseases Alias
Pthirus Pubis Infestation

Infestation By Phthirus Pubis

Crabs

Pediculosis Pubis

Pediculus Pubis

Phthiriasis Pubis

Phthirus Pubis

Phthirus/Pediculus Pubis - Pubic Lice - Crabs
Hypotrichosis 12

HYPT12

Hypotrichosis, Type 12
Coffin-Siris Syndrome 1

Coffin-Siris Syndrome

Fifth Digit Syndrome

Css

CSS1

Mrd12

Mental Retardation, Autosomal Dominant 12

Hhid

Dwarfism-Onychodysplasia

Hypertrichosis, Hyperkeratosis, Mental Retardation, And Distinctive Facial Features

Autosomal Dominant Mental Retardation 12

Short Stature-Onychodysplasia.

Intellectual Disability With Absent Fifth Fingernail And Terminal Phalanx

Mental Retardation With Hypoplastic Fifth Fingernails And Toenails

Short Stature-Onychodysplasia

Coffin-Siris Syndrome, Type 1

Mental Retardation, Autosomal Dominant, Type 12
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12188 RPL34 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus RPL34 VGNC VGNC:34116
Rattus norvegicus RPL34 RGD RGD:1309402
Felis catus RPL34 VGNC VGNC:97610
Mus musculus RPL34 MGD MGI:1915686