RPL37 - ribosomal protein L37 Gene

Homo sapiens

Also known as L37

Gene ID: 6167 | Gene type: protein coding

About RPL37

Cytogenetic location: 5p13.1 Genomic coordinates (GRCh38): 5:40,825,262-40,835,222 (from NCBI)

This gene has 6 transcripts (splice variants) and 191 orthologues. Ubiquitous expression in ovary (RPKM 354.1), bone marrow (RPKM 258.7) and 25 other tissues.

Summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L37E family of ribosomal proteins. It is located in the cytoplasm. The protein contains a C2C2-type zinc finger-like motif. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

RPL37 Products(1)

mRNA	Protein	Name
NM_000997.5	NP_000988.1	60S ribosomal protein L37

RPL37 Protein Structure

Ribosomal_L37e

0
97 a.a.

Protein Preferred Names

Protein Names

60S ribosomal protein L37

60S ribosomal protein L37a

Related Diseases

Diseases

Alias

Cataract 4, Multiple Types

Cataract 4 Multiple Types	CTRCT4
Cca3	Pcc
Aculeiform Cataract	Cataract 4, Multiple Types, With Or Without Microcornea
Cataract, Crystalline Aculeiform	Caca
Cataract, Congenital, Cerulean Type, 3	Congenital Cataract Cerulean Type 3
Cataract Congenital Dominant Non Nuclear	Ccp
Cataract, Nonnuclear Polymorphic Congenital	Cataract, Punctate, Progressive Juvenile-Onset
Cataract 4 Multiple Types With Or Without Microcornea	Autosomal Dominant Nonnuclear Polymorphic Congenital Cataract
Cataract, Polymorphic Congenital	Congenital Cataract Blue Dot Type 3
Congenital Non-Nuclear Polymorphic Cataract	Crystalline Aculeiform Cataract
Punctate, Progressive Juvenile-Onset, Cataract	Cataract, Nonnuclear Polymorphic Congenital, Autosomal Dominant

Atrial Septal Defect 2

ASD2	Atrial Heart Septal Defect 2
Atrial Septal Defect-2	Asd Ii
Septal Defect, Atrial, Type 2

Diamond-Blackfan Anemia

Congenital Pure Red Cell Aplasia	Aase Syndrome
Erythrogenesis Imperfecta	Anemia, Diamond-Blackfan
Congenital Hypoplastic Anemia	Aase-Smith Ii Syndrome
Bds	Blackfan-Diamond Anemia
Congenital Prca	Congenital Hypoplastic Anemia, Blackfan-Diamond Type
Dba	Blackfan - Diamond Syndrome
Chronic Constitutional Pure Red Cell Anaemia	Anemia Diamond Blackfan Type
Anemia Congenital Erythroid Hypoplastic	Aregenerative Anemia Chronic Congenital
Blackfan Diamond Syndrome	Red Cell Aplasia, Pure Hereditary
Aase-Smith Syndrome Ii	Bda
Blackfan Diamond Anemia	Blackfan-Diamond Disease
Blackfan-Diamond Syndrome	Chronic Congenital Agenerative Anemia
Congenital Erythroid Hypoplastic Anemia	Congenital Hypoplastic Anemia Of Blackfan And Diamond
Congenital Pure Red Cell Anemia	Hypoplastic Congenital Anemia
Inherited Erythroblastopenia	Pure Hereditary Red Cell Aplasia
Anemia, Hypoplastic, Congenital	Anemia Hypoplastic Congenital
Fanconi Anemia	Constitutional Aplastic Anemia
Diamond-Blackfan Anemia 1	Aase Smith Syndrome 2
Congenital Red Cell Aplasia	Red Cell Aplasia Of Infants
Pure Red Cell Aplasia Of Infants	Congenital Red Cell Aplastic Anaemia
Congenital Pure Red Cell Anaemia	Congenital Erythroid Hypoplasia
Pearson Marrow-Pancreas Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12193	RPL37 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS12194	RPL37A Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	RPL37	RGD	RGD:41394010
Mus musculus	RPL37	MGD	MGI:1914531

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