S100A5 - S100 calcium binding protein A5 Gene

Homo sapiens

Also known as S100D

Gene ID: 6276 | Gene type: protein coding

About S100A5

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:153,537,147-153,543,685 (from NCBI)

This gene has 2 transcripts (splice variants), 351 orthologues and 21 paralogues. Low expression observed in reference dataset.

Summary

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has a Ca2+ affinity 20- to 100-fold higher than the other S100 proteins studied under identical conditions. This protein also binds Zn2+ and Cu2+, and Cu2+ strongly which impairs the binding of Ca2+. This protein is expressed in very restricted regions of the adult brain. [provided by RefSeq, Jul 2008]

S100A5 Products(4)

mRNA	Protein	Name
NM_001394232.1	NP_001381161.1	protein S100-A5
NM_001394233.1	NP_001381162.1	protein S100-A5
NM_001394234.1	NP_001381163.1	protein S100-A5
NM_002962.2	NP_002953.2	protein S100-A5

S100A5 Protein Structure

S_100

0
92 a.a.

Protein Preferred Names

Protein Names

protein S100-A5

Related Diseases

Diseases

Alias

Epidermoid Cysts

Epidermoid Cyst	Sebaceous Cyst
Epidermal Inclusion Cyst	Epidermal Cyst

Anaplastic Astrocytoma

Grade Iii Astrocytoma	Astrocytoma, Anaplastic
Grade Iii Astrocytic Tumor

Meningioma, Familial

Meningioma	Familial Meningioma
Meningioma, Familial, Susceptibility To	Meningeal Neoplasm
Meningeal Neoplasms	Meningiomas
Meningioma, Nf2-Related, Somatic	Meningioma, Sis-Related
Meningothelial Cell Tumor	Neoplasm Of The Meninges
Primary Meningeal Tumor	Familial Multiple Meningioma
MNGMA	Meningioma, Benign, No Icd-O Subtype
Intracranial Meningioma	Meningothelial Cell Neoplasm
Supratentorial Meningioma	Primary Neoplasm Of Spinal Meninges
Benign Intracranial Meningioma	Benign Meningioma
Meningeal Tumours	Meningeal Sarcoma Of Unspecified Site
Meningothelial Sarcoma Of Unspecified Site

Pulmonary Systemic Sclerosis

Lung Disease With Systemic Sclerosis

Lung Involvement In Systemic Sclerosis

Psoriasis 7

PSORS7	Psoriasis 7, Susceptibility To
Psoriasis Susceptibility 7	Psoriasis
Psoriasis Vulgaris	Pv

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12381	S100A5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	S100A5	MGD	MGI:1338915
Felis catus	S100A5	VGNC	VGNC:64841
Canis familiaris	S100A5	VGNC	VGNC:45831
Rattus norvegicus	S100A5	RGD	RGD:1308996
Bos taurus	S100A5	VGNC	VGNC:34245
Macaca mulatta	S100A5	VGNC	VGNC:76959
Others	S100A5	NCBI

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