2. Gene
  3. DMRTA2 - DMRT like family A2 Gene

DMRTA2 - DMRT like family A2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 63950 | Gene type: protein coding

About DMRTA2

Cytogenetic location: 1p32.3 Genomic coordinates (GRCh38): 1:50,417,550-50,423,443 (from NCBI)

This gene has 2 transcripts (splice variants), 185 orthologues and 8 paralogues. Low expression observed in reference dataset.

Summary

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II and sex differentiation. Predicted to act upstream of or within nervous system development and skeletal muscle cell differentiation. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

DMRTA2 Products(1)

mRNA Protein Name
NM_032110.3 NP_115486.1 doublesex- and mab-3-related transcription factor A2

DMRTA2 Protein Structure

DM

DM: DM DNA binding domain (66 - 112)

DMA

DMA: DMRTA motif (313 - 351)

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  • 542 a.a.
Protein Preferred Names Protein Names

doublesex- and mab-3-related transcription factor A2

doublesex- and mab-3-related transcription factor 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03832 DMRTA2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus DMRTA2 MGD MGI:2653629
Macaca mulatta DMRTA2 VGNC VGNC:106349
Felis catus DMRTA2 VGNC VGNC:107523
Bos taurus DMRTA2 VGNC VGNC:28114
Rattus norvegicus DMRTA2 RGD RGD:1308173