SRSF6 - serine and arginine rich splicing factor 6 Gene

Homo sapiens

Also known as B52; SFRS6; SRP55; HEL-S-91

Gene ID: 6431 | Gene type: protein coding

About SRSF6

Cytogenetic location: 20q13.11 Genomic coordinates (GRCh38): 20:43,457,896-43,464,243 (from NCBI)

This gene has 6 transcripts (splice variants), 260 orthologues and 8 paralogues. Ubiquitous expression in bone marrow (RPKM 64.4), prostate (RPKM 51.8) and 25 other tissues.

Summary

The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. Alternative splicing results in multiple transcript variants. In addition, two pseudogenes, one on chromosome 17 and the other on the X chromosome, have been found for this gene.[provided by RefSeq, Sep 2010]

SRSF6 Products(1)

mRNA	Protein	Name
NM_006275.6	NP_006266.2	serine/arginine-rich splicing factor 6

SRSF6 Protein Structure

RRM_1

0
100
200
300
344 a.a.

Protein Preferred Names

Protein Names

serine/arginine-rich splicing factor 6

SR splicing factor 6

Related Diseases

Diseases

Alias

Plasmodium Malariae Malaria

Quartan Malaria	Malaria By Plasmodium Malariae
Nephrotic Syndrome Of Quartan Malaria	Malaria Nephrosis
Malarial Nephrosis	Nephrotic Syndrome In Malaria
Quartan Nephrosis

Aortitis

Cataract 30

Cataract 30 Pulverulent	Cataract Coppock-Like
Ctrct30	Dusty Cataract
Cataract, Type 30

Temporal Arteritis

Polymyalgia Rheumatica	Giant Cell Arteritis
Cranial Arteritis	Horton Disease
Gca	Horton'S Disease
Rhizomelic Pseudopolyarthritis	Arteritis Cranialis
Arteritis Temporalis	Horton'S Arteritis
Horton'S Giant Cell Arteritis	Horton'S Temporal Arteritis
Horton'S Syndrome	Gca - [Giant Cell Arteritis]
Senile Arthritis	Polymyalgia Arteritica
Pmr - [Polymyalgia Rheumatica]	Forestier-Certonciny Syndrome
Rheumatic Polymyalgia	Polymyalgia

Aortic Valve Insufficiency

Aortic Regurgitation	Rheumatic Aortic Regurgitation
Aortic Insufficiency	Rheumatic Aortic Insufficiency
Rheumatic Aortic Valve Insufficiency	Aortic Incompetence
Corrigan'S Disease	Rheumatic Aortic Valve Regurgitation
Aortic Valve Incompetency	Ai - [Aortic Incompetence]
Incompetent Aortic Valve	Ar - [Aortic Regurgitation]
Calcific Aortic Valve Regurgitation	Myxomatous Aortic Valve Regurgitation
Annular Incompetency Of Aortic Valve	Austin Flint Murmur
Flint Murmur	Rheumatic Aortic Incompetence
Rheumatic Ai - [Aortic Insufficiency]

Denys-Drash Syndrome

Drash Syndrome	DDS
Nephropathy, Wilms Tumor, And Genital Anomalies	Wilms Tumor And Pseudohermaphroditism
Wilms Tumor And Pseudo- Or True Hermaphroditism	Nephropathy Associated With Male Pseudohermaphroditism And Wilms' Tumor
Pseudohermaphroditism, Nephron Disorder And Wilms' Tumor	Wilms Tumor-Dsd Syndrome
Wilms Tumor-Disorder Of Sex Development Syndrome

Behcet Syndrome

Behcet Disease	Behcet'S Syndrome
Behcet'S Disease	Behçet Disease
Bd	Adamantiades-Behcet Disease
Triple Symptom Complex	Behçet'S Disease
Behet'S Syndrome	Bd Syndrome
Behçet Syndrome	Behçet'S Syndrome
Behcet Triple Symptom Complex	Malignant Aphthosis
Old Silk Route Disease	Adamantiades-Behçet Disease

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13797	SRSF6 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	SRSF6	VGNC	VGNC:54735
Mus musculus	SRSF6	MGD	MGI:1915246
Rattus norvegicus	SRSF6	RGD	RGD:1359241
Bos taurus	SRSF6	VGNC	VGNC:57028
Macaca mulatta	SRSF6	VGNC	VGNC:77821

Name
Email *

	Sorry, but the email address you supplied was invalid.