NOM1 - nucleolar protein with MIF4G domain 1 Gene

Homo sapiens

Also known as SGD1; C7orf3; PPP1R113

Gene ID: 64434 | Gene type: protein coding

About NOM1

Cytogenetic location: 7q36.3 Genomic coordinates (GRCh38): 7:156,949,712-156,973,176 (from NCBI)

This gene has 8 transcripts (splice variants), 183 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 2.9), lymph node (RPKM 2.8) and 25 other tissues.

Summary

Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and/or MA3 domains, such as NOM1, function in protein translation. These domains include binding sites for members of the EIF4A family of ATP-dependent DEAD box RNA helicases (see EIF4A1; MIM 602641) (Simmons et al., 2005 [PubMed 15715967]).[supplied by OMIM, Mar 2008]

NOM1 Products(2)

mRNA	Protein	Name
NM_001353366.2	NP_001340295.1	nucleolar MIF4G domain-containing protein 1 isoform 2
NM_138400.2	NP_612409.1	nucleolar MIF4G domain-containing protein 1 isoform 1

NOM1 Protein Structure

MIF4G

MA3

0
200
400
600
800
860 a.a.

Protein Preferred Names

Protein Names

nucleolar MIF4G domain-containing protein 1

SGD1 homolog

Related Diseases

Diseases

Alias

Neuronopathy, Distal Hereditary Motor, Type I

Dhmn1	Hmn I
Distal Hereditary Motor Neuronopathy Type 1	Autosomal Dominant Distal Juvenile Spinal Muscular Atrophy Type 1
Neuronopathy, Distal Hereditary Motor, Type 1	HMN1
Neuropathy, Distal Hereditary Motor, Type I	Spinal Muscular Atrophy, Distal, Juvenile, Autosomal Dominant, I
Charcot-Marie-Tooth Disease, Spinal, I	Distal Hereditary Motor Neuropathy Type I
Spinal Charcot-Marie-Tooth Disease 1	Distal Hereditary Motor Neuropathy Type 1
Neuropathy, Motor, Distal, Hereditary, Type I

Acheiropody

Acheiropodia	ACHP
Acheiropody, Brazilian Type	Horn-Kolb Syndrome
Horn Kolb Syndrome	Acheiropody Brazilian Type

Ovarian Mucinous Adenocarcinoma

Mucinous Carcinoma Of Ovary

Polydactyly

Non-Syndromic Polydactyly	Polydactyly, Postaxial
Postaxial Polydactyly	Supernumerary Digit
Extra Digits	Hyperdactyly
Polydactylia	Polydactylism
Supernumerary Digits

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09421	NOM1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	NOM1	VGNC	VGNC:81729
Mus musculus	NOM1	MGD	MGI:1861749
Rattus norvegicus	NOM1	RGD	RGD:1588109
Felis catus	NOM1	VGNC	VGNC:63855
Bos taurus	NOM1	VGNC	VGNC:32162