2. Gene
  3. MRPS9 - mitochondrial ribosomal protein S9 Gene

MRPS9 - mitochondrial ribosomal protein S9 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as S9mt; RPMS9; MRP-S9

Gene ID: 64965 | Gene type: protein coding

About MRPS9

Cytogenetic location: 2q12.1 Genomic coordinates (GRCh38): 2:105,038,069-105,099,960 (from NCBI)

This gene has 3 transcripts (splice variants), 215 orthologues and 1 paralogue. Ubiquitous expression in heart (RPKM 14.5), testis (RPKM 14.4) and 25 other tissues.

Summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. [provided by RefSeq, Jul 2008]

MRPS9 Products(1)

mRNA Protein Name
NM_182640.3 NP_872578.1 28S ribosomal protein S9, mitochondrial

MRPS9 Protein Structure

Ribosomal_S9

Ribosomal_S9: Ribosomal protein S9/S16 (274 - 396)

  • 0
  • 100
  • 200
  • 300
  • 396 a.a.
Protein Preferred Names Protein Names

28S ribosomal protein S9, mitochondrial

mitochondrial small ribosomal subunit protein uS9m

Related Diseases

Diseases Alias
Megalencephalic Leukoencephalopathy With Subcortical Cysts 1

Van Der Knaap Disease

Leukoencephalopathy With Swelling And Cysts

MLC1

Vacuolating Megalencephalic Leukoencephalopathy With Subcortical Cysts

Lvm

Vl

Leukoencephalopathy, Megalencephalic, With Subcortical Cysts, 1

Leukoencephalopathy, Megalencephalic, With Subcortical Cysts, Type 1

Megalencephalic Leukoencephalopathy With Subcortical Cysts
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08690 MRPS9 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris MRPS9 VGNC VGNC:43427
Bos taurus MRPS9 VGNC VGNC:31678
Macaca mulatta MRPS9 VGNC VGNC:74762
Mus musculus MRPS9 MGD MGI:1916777
Rattus norvegicus MRPS9 RGD RGD:1306558
Felis catus MRPS9 VGNC VGNC:81124