2. Gene
  3. Ido1 - indoleamine 2,3-dioxygenase 1 Gene

Ido1 - indoleamine 2,3-dioxygenase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Ido; Indo

Gene ID: 66029 | Gene type: protein coding

About Ido1

Primary_assembly 16: 67,430,578-67,442,730 forward strand.mRatBN7.2:CM026989.1

This gene has 2 transcripts (splice variants), 98 orthologues and is associated with 32 phenotypes. Biased expression in Thymus (RPKM 11.8), Testes (RPKM 2.9) and 2 other tissues.

Summary

Enables amino acid binding activity; indoleamine 2,3-dioxygenase activity; and oxygen binding activity. Involved in tryptophan catabolic process to kynurenine. Located in cytosol. Orthologous to human IDO1 (indoleamine 2,3-dioxygenase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ido1 Products(1)

mRNA Protein Name
NM_023973.2 NP_076463.2 indoleamine 2,3-dioxygenase 1
Protein Preferred Names Protein Names

indoleamine 2,3-dioxygenase 1

IDO-1

indoleamine 23-dioxygenase

indoleamine-pyrrole 2,3-dioxygenase

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0110 Palmatine chloride Inhibitor 99.77% Unkown
HY-N0110A Palmatine Inhibitor / Unkown
Clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-15689 Epacadostat Inhibitor 99.66% Phase 3
HY-101560 Linrodostat Inhibitor 99.89% Phase 3
HY-101111 PF-06840003 Inhibitor 99.95% Phase 1
Pre-clinical Phase
Bioactive Molecules (29)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13983 IDO-IN-7 Inhibitor 99.98% Unkown
HY-148383 DP00477 Inhibitor 99.03% Unkown
HY-151108 IDO1/TDO-IN-4 Inhibitor 99.23% Unkown
HY-N0110B Palmatine hydroxide Inhibitor 99.64% Unkown
HY-111540 LY-3381916 Inhibitor 99.54% Unkown
HY-131911 PROTAC IDO1 Degrader-1 Inhibitor 98.17% Unkown
HY-151093 IDO2-IN-1 Inhibitor 98.86% Unkown
HY-18769 BMS-978587 Inhibitor 99.92% Unkown
HY-139204 BMS-986242 Inhibitor 99.42% Unkown
HY-112147 IDO1 and HDAC1 Inhibitor Inhibitor / Unkown
HY-145280 IDO1/2-IN-1 Inhibitor 98.06% Unkown
HY-120742 MMG-0358 Inhibitor / Unkown
HY-144778 IDO1/TDO-IN-1 Inhibitor / Unkown
HY-147772 ZC0101 Inhibitor / Unkown
HY-144468 IDO1-IN-17 Inhibitor / Unkown
HY-144466 IDO1-IN-16 Inhibitor / Unkown
HY-158334 NDs-IN-1 Inhibitor / Unkown
HY-130607 IDO1-IN-2 Inhibitor / Unkown
HY-154387 1-Isopropyltryptophan Inhibitor / Unkown
HY-144652 IDO1-IN-19 Inhibitor 98.52% Unkown
HY-144274 IDO1-IN-14 Inhibitor / Unkown
HY-144273 IDO1-IN-13 Inhibitor / Unkown
HY-149227 IDO1-IN-21 Inhibitor / Unkown
HY-148572 NAMPT/IDO1-IN-1 Inhibitor / Unkown
HY-161348 AT-0174 Inhibitor / Unkown
HY-D0033 Roxyl-9 Inhibitor 99.22% Unkown
HY-144465 IDO1-IN-15 Inhibitor / Unkown
HY-151886 NU223612 Inhibitor / Unkown
HY-78699 2-Hydrazinobenzothiazole Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ido1 NCBI NCBI:3620