SOX15 - SRY-box transcription factor 15 Gene

Homo sapiens

Also known as SOX20; SOX26; SOX27

Gene ID: 6665 | Gene type: protein coding

About SOX15

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:7,588,178-7,590,094 (from NCBI)

This gene has 3 transcripts (splice variants), 281 orthologues and 20 paralogues. Biased expression in skin (RPKM 12.3), esophagus (RPKM 6.9) and 8 other tissues.

Summary

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. [provided by RefSeq, Jul 2008]

SOX15 Products(1)

mRNA	Protein	Name
NM_006942.2	NP_008873.1	protein SOX-15

SOX15 Protein Structure

HMG_box

0
100
200
233 a.a.

Protein Preferred Names

Protein Names

protein SOX-15

SRY (sex determining region Y)-box 15

Related Diseases

Diseases

Alias

Acromesomelic Dysplasia 2a

Chondrodysplasia, Grebe Type	Acromesomelic Dysplasia, Grebe Type
Grebe Chondrodysplasia	Amdg
Grebe Syndrome	AMD2A
Grebe Dysplasia	Achondrogenesis, Brazilian
Achondrogenesis, Type Ii, Formerly	Acromesomelic Dysplasia-2a
Achondrogenesis Type Ii	Brazilian Achondrogenesis
Acromesomelic Chondrodysplasia, Grebe Type

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13588	SOX15 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SOX15	MGD	MGI:98363
Macaca mulatta	SOX15	VGNC	VGNC:104658
Bos taurus	SOX15	VGNC	VGNC:35143
Felis catus	SOX15	VGNC	VGNC:65580
Rattus norvegicus	SOX15	RGD	RGD:1312022
Canis familiaris	SOX15	VGNC	VGNC:46675

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