2. Gene
  3. Brd3 - bromodomain containing 3 Gene

Brd3 - bromodomain containing 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as ORFX; Fsrg2; RINGL3; 2410084F24Rik

Gene ID: 67382 | Gene type: protein coding

About Brd3

Chromosome 2: 27,335,591-27,397,674 reverse strand.GRCm39:CM000995.3

This gene has 10 transcripts (splice variants), 150 orthologues and 11 paralogues. Ubiquitous expression in CNS E11.5 (RPKM 15.9), limb E14.5 (RPKM 14.1) and 28 other tissues.

Summary

Predicted to enable lysine-acetylated histone binding activity and nucleosomal histone binding activity. Predicted to be involved in chromatin remodeling and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within chromatin organization. Predicted to be active in chromatin and nucleus. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; hemolymphoid system; and retina. Orthologous to human BRD3 (bromodomain containing 3). [provided by Alliance of Genome Resources, Apr 2022]

Brd3 Products(3)

mRNA Protein Name
NM_001113574.1 NP_001107046.1 bromodomain-containing protein 3 isoform 1
NM_023336.4 NP_075825.3 bromodomain-containing protein 3 isoform 2
NM_001113573.1 NP_001107045.1 bromodomain-containing protein 3 isoform 2

Brd3 Protein Structure

Bromo_Brdt_I_like

Bromo_Brdt_I_like: cd05497 (32 - 138)

Bromo_Brdt_II_like

Bromo_Brdt_II_like: cd05498 (309 - 410)

BET

BET: pfam17035 (571 - 635)

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  • 726 a.a.
Protein Preferred Names Protein Names

bromodomain-containing protein 3

bromodomain-containing FSH-like protein FSRG2

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-112090 ABBV-744 Inhibitor 99.97% Phase 1
Pre-clinical Phase
Bioactive Molecules (19)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100972 ARV-771 Inhibitor 99.87% Unkown
HY-136570 GSK778 Inhibitor 98.93% Unkown
HY-136571 GSK046 Inhibitor 99.65% Unkown
HY-101519 BETd-260 Inhibitor 99.59% Unkown
HY-141438 SIM1 Inhibitor 99.72% Unkown
HY-120000 MS402 Inhibitor 99.62% Unkown
HY-112429 HJB97 Inhibitor 98.24% Unkown
HY-130622 LT052 Inhibitor 98.77% Unkown
HY-114504 RVX-297 Inhibitor 96.59% Unkown
HY-114416 GS-626510 Inhibitor 99.80% Unkown
HY-112610 CF53 Inhibitor 99.78% Unkown
HY-131061 BET bromodomain inhibitor 1 Inhibitor 99.91% Unkown
HY-145264 OARV-771 Inhibitor 98.33% Unkown
HY-138563 GSK973 Inhibitor 99.46% Unkown
HY-126325 BY27 Inhibitor / Unkown
HY-152213 BET-IN-13 Inhibitor / Unkown
HY-110215 XD14 Inhibitor 95.02% Unkown
HY-155680 BET BD2-IN-1 Inhibitor / Unkown
HY-136570A GSK778 hydrochloride Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Brd3 NCBI NCBI:8019