SULT1E1 - sulfotransferase family 1E member 1 Gene

Homo sapiens

Also known as EST; STE; EST-1; ST1E1

Gene ID: 6783 | Gene type: protein coding

About SULT1E1

Cytogenetic location: 4q13.3 Genomic coordinates (GRCh38): 4:69,821,122-69,860,145 (from NCBI)

This gene has 2 transcripts (splice variants), 616 orthologues and 12 paralogues. Biased expression in small intestine (RPKM 11.9), duodenum (RPKM 11.7) and 4 other tissues.

Summary

Sulfotransferase enzymes catalyze the sulfate conjugation of many Hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors. [provided by RefSeq, Jul 2008]

SULT1E1 Products(1)

mRNA	Protein	Name
NM_005420.3	NP_005411.1	sulfotransferase 1.00E+01

SULT1E1 Protein Structure

Sulfotransfer_1

0
100
200
294 a.a.

Protein Preferred Names

Protein Names

sulfotransferase 1E1

estrogen sulfotransferase

Recombinant SULT1E1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76099	SULT1E1 Protein, Human (His)	P49888 (N2-I294)	≥95%

Related Diseases

Diseases

Alias

Endometrial Cancer

Endometrial Carcinoma	Endometrial Neoplasm
Malignant Neoplasm Of Endometrium	Endometrioid Carcinoma
Endometrial Neoplasms	Carcinoma, Endometrioid
Endometrial Cancer, Familial	Endometrial Carcinoma, Somatic
Endometrial Cancer, Susceptibility To	Endometrial Ca
Malignant Endometrial Neoplasm	Neoplasm Of Endometrium
Primary Malignant Neoplasm Of Endometrium	Tumor Of Endometrium
Carcinoma Of The Endometrium	Endometrioid Carcinoma Of Female Reproductive System
ENDMC	Carcinoma Endometrioid
Endometrial Cancers	Cancer, Endometrial
Uterine Corpus Cancer

Skin Angiosarcoma

Angiosarcoma Of Skin	Hemangiosarcoma Of The Skin
Haemangiosarcoma Of Skin	Lymphangiosarcoma Of Skin
Cutaneous Angiosarcoma	Malignant Haemangioendothelioma Of Skin

Estrogen Excess

Hyperestrogenism

Clear Cell Adenoma

Breast Cancer

Breast Carcinoma	Male Breast Cancer
Breast Cancer, Familial	Malignant Neoplasm Of Breast
Breast Cancer, Susceptibility To	Breast Cancer, Early-Onset
Malignant Tumor Of Breast	Carcinoma Of Male Breast
Breast Cancer, Invasive Ductal	Breast Cancer, Protection Against
Breast Cancer, Somatic	Breast Cancer, Male
Breast Cancer, Lobular, Somatic	Breast Tumor
Mammary Cancer	Mammary Tumor
Malignant Neoplasm Of Male Breast	Mammary Carcinoma
Male Breast Carcinoma	Familial Cancer Of Breast
Invasive Ductal Breast Carcinoma	Breast Cancer Susceptibility
Breast Cancer, Male, Susceptibility To	Breast Cancer, Early-Onset, Susceptibility To
Malignant Tumor Of The Breast	Mammary Neoplasm
Primary Breast Cancer	Neoplasm Of Male Breast
Carcinoma Of Breast	Breast Cancer In Men
Familial Breast Cancer	Cancer Of Breast
BC	Breast Cancer Familial
Breast Cancer Familial Male	Breast Cancer, Familial Male
Breast Male Carcinoma	Breast Neoplasms
Breast Neoplasms, Male	Mammary Tumors
Mammary Carcinomas	Cancer, Breast
Cancer, Breast, Susceptibility	Invasive Breast Ductal Carcinoma
Breast Neoplasm	Susceptibility To Breast Cancer
Mammary Neoplasms	Animal Mammary Neoplasms
Primary Malignant Neoplasm Of Breast	Infiltrating Ductal Carcinoma Of Breast
Infiltrating Duct Carcinoma Of Unspecified Site	Infiltrating Ductular Carcinoma Of Unspecified Site
Invasive Breast Carcinoma Of No Special Type	Microinvasive Carcinoma Of Breast
Carcinoma With Apocrine Differentiation

Breast Disease

Breast Diseases

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14019	SULT1E1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	SULT1E1	MGD	MGI:98431
Rattus norvegicus	SULT1E1	RGD	RGD:3776
Macaca mulatta	SULT1E1	VGNC	VGNC:100275
Bos taurus	SULT1E1	VGNC	VGNC:35467
Others	SULT1E1	NCBI

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