2. Gene
  3. SURF4 - surfeit 4 Gene

SURF4 - surfeit 4 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as ERV29

Gene ID: 6836 | Gene type: protein coding

About SURF4

Cytogenetic location: 9q34.2 Genomic coordinates (GRCh38): 9:133,361,464-133,377,949 (from NCBI)

This gene has 9 transcripts (splice variants), 1 gene allele, 252 orthologues and 1 paralogue. Ubiquitous expression in duodenum (RPKM 40.0), small intestine (RPKM 39.7) and 25 other tissues.

Summary

This gene is located in the surfeit gene cluster, which is comprised of very tightly linked housekeeping genes that do not share sequence similarity. The encoded protein is a conserved integral membrane protein that interacts with endoplasmic reticulum-Golgi intermediate compartment proteins. Disruption of this gene results in reduced numbers of endoplasmic reticulum-Golgi intermediate compartment clusters and redistribution of coat protein I to the cytosol. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

SURF4 Products(7)

mRNA Protein Name
NM_001280788.2 NP_001267717.1 surfeit locus protein 4 isoform 2
NM_001280789.2 NP_001267718.1 surfeit locus protein 4 isoform 3
NM_001280790.2 NP_001267719.1 surfeit locus protein 4 isoform 4
NM_001280791.2 NP_001267720.1 surfeit locus protein 4 isoform 4
NM_001280792.2 NP_001267721.1 surfeit locus protein 4 isoform 5
NM_001280793.2 NP_001267722.1 surfeit locus protein 4 isoform 6
NM_033161.4 NP_149351.1 surfeit locus protein 4 isoform 1

SURF4 Protein Structure

SURF4

SURF4: SURF4 family (4 - 269)

  • 0
  • 100
  • 200
  • 269 a.a.
Protein Preferred Names Protein Names

surfeit locus protein 4

surface 4 integral membrane protein

Related Diseases

Diseases Alias
Colorectal Cancer, Hereditary Nonpolyposis, Type 2

HNPCC2

Fcc2

Coca2

Hereditary Nonpolyposis Colorectal Cancer Type 2

Colon Cancer, Familial Nonpolyposis, Type 2

Familial Nonpolyposis Colon Cancer Type 2

Hereditary Non-Polyposis Colorectal Cancer 2

Cancer, Colorectal, Nonpolyposis, Hereditary, Type 2
Macular Degeneration, Age-Related, 4

Age Related Macular Degeneration 4

ARMD4

Macular Degeneration, Age-Related, Type 4
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14044 SURF4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus SURF4 VGNC VGNC:106962
Rattus norvegicus SURF4 RGD RGD:1561980
Felis catus SURF4 VGNC VGNC:102990
Canis familiaris SURF4 VGNC VGNC:46996
Mus musculus SURF4 MGD MGI:98445
Macaca mulatta SURF4 VGNC VGNC:78060