ERBB3 - erb-b2 receptor tyrosine kinase 3 Gene

Macaca mulatta

Gene ID: 711407 | Gene type: protein coding

About ERBB3

Primary_assembly 11: 55,641,371-55,673,299 forward strand.Mmul_10:CM014346.1

This gene has 6 transcripts (splice variants), 280 orthologues and 53 paralogues.

mRNA	Protein	Name
XM_015151940.2	XP_015007426.2	receptor tyrosine-protein kinase erbB-3 isoform X1
XM_028829604.1	XP_028685437.1	receptor tyrosine-protein kinase erbB-3 isoform X2

Recep_L_domain

Furin-like

Recep_L_domain

GF_recep_IV

TM_ErbB3

PTK_HER3

Protein Preferred Names

Protein Names

receptor tyrosine-protein kinase erbB-3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3

Cat. No.	Product Name	Accession	Purity
HY-P76967	HER3 Protein, Rhesus Macaque (HEK293)	XP_001113953.2 (S20-T643)	≥95%
HY-P76968	HER3 Protein, Rhesus Macaque (HEK293, Fc)	XP_001113953.2 (S20-T643)	≥95%
HY-P76969	HER3 Protein, Rhesus Macaque (HEK293, His)	XP_001113953.2 (S20-T643)	≥95%

Clinical Phase

Inhibitory Antibodies (6)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99275	Patritumab	Inhibitor	98.94%	Phase 3
HY-P99268	Seribantumab		≥95.0%	Phase 2
HY-P99866	Duligotuzumab		97.93%	Phase 2
HY-P99672	Istiratumab	Inhibitor	/	Phase 2
HY-P99304	Lumretuzumab	Inhibitor	95.00%	Phase 1
HY-P99461	Barecetamab	Inhibitor	97.96%	Phase 1

Pre-clinical Phase

Bioactive Molecules (7)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-13050	Sapitinib	Inhibitor	99.93%	Unkown
HY-100848	TX1-85-1	Inhibitor	98.04%	Unkown
HY-18609	PD158780	Inhibitor	99.56%	Unkown
HY-118998	TX2-121-1	Inhibitor	/	Unkown
HY-RS04469	ERBB3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS04470	Erbb3 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS04471	Erbb3 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	ERBB3	NCBI	NCBI:2065
Mus musculus	ERBB3	NCBI	NCBI:13867
Rattus norvegicus	ERBB3	NCBI	NCBI:29496

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